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Part 1: Document Description
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Citation |
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Title: |
Replication Data for: Plasmodium falciparum adapts investment into replication versus reproduction transmission according to host environment |
Identification Number: |
doi:10.7910/DVN/BXXVRY |
Distributor: |
Harvard Dataverse |
Date of Distribution: |
2022-11-17 |
Version: |
2 |
Bibliographic Citation: |
Abdi, Abdirahman I.; Achcar, Fiona; Sollelis, Lauriane; Silva-Filho, Joao L.; Mwikali, Kioko; Muthui, Michelle; Mwangi, Shaban; Kimingi, Hannah W.; Orindi, Benedict; Kivisi, Cheryl Andisi; Alkema,Manon; Chandrasekar, Amrita; Bull, Peter C.; Bejon,Philip; Modrzynska,Kaarzyna; Bousema, Teun; Marti, Matthias, 2022, "Replication Data for: Plasmodium falciparum adapts investment into replication versus reproduction transmission according to host environment", https://doi.org/10.7910/DVN/BXXVRY, Harvard Dataverse, V2, UNF:6:uD14tRF+X1o1d56q2BdgGg== [fileUNF] |
Citation |
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Title: |
Replication Data for: Plasmodium falciparum adapts investment into replication versus reproduction transmission according to host environment |
Identification Number: |
doi:10.7910/DVN/BXXVRY |
Authoring Entity: |
Abdi, Abdirahman I. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
Achcar, Fiona (Wellcome Center for Integrative Parasitology, Institute of Infection and Immunity, University of Glasgow, Glasgow. Scotland, UK) |
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Sollelis, Lauriane (Wellcome Center for Integrative Parasitology, Institute of Infection and Immunity, University of Glasgow, Glasgow. Scotland, UK) |
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Silva-Filho, Joao L. (Wellcome Center for Integrative Parasitology, Institute of Infection and Immunity, University of Glasgow, Glasgow. Scotland, UK) |
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Mwikali, Kioko (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Muthui, Michelle (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Mwangi, Shaban (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Kimingi, Hannah W. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Orindi, Benedict (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Kivisi, Cheryl Andisi (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Alkema,Manon (Radboud University Medical Center, Nijmegen, The Netherlands) |
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Chandrasekar, Amrita (Wellcome Center for Integrative Parasitology, Institute of Infection and Immunity, University of Glasgow, Glasgow. Scotland, UK) |
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Bull, Peter C. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Bejon,Philip (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Modrzynska,Kaarzyna (Wellcome Center for Integrative Parasitology, Institute of Infection and Immunity, University of Glasgow, Glasgow. Scotland, UK) |
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Bousema, Teun (Radboud University Medical Center, Nijmegen, The Netherlands) |
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Marti, Matthias (Wellcome Center for Integrative Parasitology, Institute of Infection and Immunity, University of Glasgow, Glasgow. Scotland, UK) |
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Distributor: |
Harvard Dataverse |
Access Authority: |
Abdi, Abdirahman I. |
Depositor: |
Abdi, Abdirahman I. |
Date of Deposit: |
2022-11-09 |
Holdings Information: |
https://doi.org/10.7910/DVN/BXXVRY |
Study Scope |
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Keywords: |
Medicine, Health and Life Sciences |
Abstract: |
<p>The dataset contains sequence data used to publish findings in the manuscript titled: "<a href="">Plasmodium falciparum adapts investment into replication versus reproduction transmission according to host environment</a>" submitted to ELife Journal.</p> <p>The data was generated to investigate the impact of host inflammatory response on the infecting malaria parasites. The study used clinical data collected from children presenting with malaria (1994-2014), gene transcription (ap2g, pfsir2a, pfs16) of the parasites isolated from the children, plasma level of PfHRP2, 34 inflammatory markers and lipidome</p> |
Kind of Data: |
Restricted Access |
Notes: |
<p><strong>Data Access: </strong>Restricted</p> <p>Access to these data requires submission of a formal request for consideration by our Data Governance Committee. </p> <strong>How to request</strong> <ol> <li>Download and complete the <a href="https://kemri-wellcome.org/zp-content/uploads/2021/02/KWTRP_Dataverse_Data_Request_Form_2019.docx"><strong>data request form</strong></a></li> <li> Email completed data request form to the Data Governance Committee at <a href="mailto:dgc@kemri-wellcome.org?cc=lmwango@kemri-wellcome.org?Subject=Data%20Access%20Request"><strong>dgc@kemri-wellcome.org</strong></a> </li> </ol> <p><strong>License: </strong><a href="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</a> <a href="https://creativecommons.org/licenses/by/4.0/legalcode"><img src="https://i.creativecommons.org/l/by/3.0/88x31.png"> </a></p> |
Methodology and Processing |
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Sources Statement |
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Data Access |
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Citation Requirement: |
<p>Publications based on this data collection should acknowledge this source by means of bibliographic citation.</p> |
Notes: |
<p>This data is licensed under the <a href="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</a> <a href="https://creativecommons.org/licenses/by/4.0/legalcode"><img src="https://i.creativecommons.org/l/by/3.0/88x31.png"> </a> </p> |
For access to restricted data, there is a process of managed access requiring submission of a request form for consideration by our Data Governance Committee. Please send a signed data request form to [<a href="mailto:dgc@kemri-wellcome.org">dgc@kemri-wellcome.org</a> ]. <strong> <a href="https://kemri-wellcome.org/zp-content/uploads/2021/02/KWTRP_Dataverse_Data_Request_Form_2019.docx">Click to download Data Request Form</a></strong> |
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Other Study Description Materials |
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File Description--f6710229 |
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File: Final_groups_with_batch.tab |
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Notes: |
UNF:6:Hoba/XyhK+M/52ProJVMSQ== |
File Description--f6710228 |
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File: lipidomics_idsAnnot.tab |
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Notes: |
UNF:6:SfU6/sxLnVAeIRT5Epla1Q== |
File Description--f6710218 |
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File: malaria_positives_and_mean_age.tab |
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Notes: |
UNF:6:pkBchAA6fylxWvKo8OXPaA== |
List of Variables: | |
Variables |
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f6710229 Location: |
Variable Format: character Notes: UNF:6:vkpyw2QUqoSjMmazHYqOmA== |
f6710229 Location: |
Summary Statistics: Mean 2008.375; StDev 4.558981654436678; Valid 256.0; Min. 1995.0; Max. 2012.0; Variable Format: numeric Notes: UNF:6:50Z1e2z8hQIpkw4Wi8GuRg== |
f6710229 Location: |
Variable Format: character Notes: UNF:6:h7TsjoWIG/t7wcSq0fOcbg== |
f6710229 Location: |
Summary Statistics: Valid 269.0; Mean 38.331970275092935; Min. 35.099998; StDev 1.1554301129540523; Max. 40.799999 Variable Format: numeric Notes: UNF:6:usvswe9BJI7TRGPhg07BlA== |
f6710229 Location: |
Summary Statistics: Mean 4.95006016616829; Max. 6.18202669589275; StDev 0.8611052645283892; Min. 0.0; Valid 241.0; Variable Format: numeric Notes: UNF:6:JzUL4XxE47Zf9TjusKyGSQ== |
f6710229 Location: |
Summary Statistics: Max. 4.9025669; StDev 1.7317626244975235; Min. -4.9416456; Valid 269.0; Mean 0.23825186275873605 Variable Format: numeric Notes: UNF:6:pxyk1F341e2FzQgw2AE4hQ== |
f6710229 Location: |
Variable Format: character Notes: UNF:6:OohAQdkjYjubbE7CXSi14Q== |
f6710229 Location: |
Variable Format: character Notes: UNF:6:F51td3I5j3E9HypszXzo1Q== |
f6710228 Location: |
Variable Format: character Notes: UNF:6:ewpU8mRTetyffoN41xZRfA== |
f6710228 Location: |
Variable Format: character Notes: UNF:6:QR0nGYriv0CbjK6cXg+oMA== |
f6710228 Location: |
Variable Format: character Notes: UNF:6:AKwknoEIzHT8TRdCpk4Bsg== |
f6710228 Location: |
Variable Format: character Notes: UNF:6:W1RJ8MOs6xxQn0PvRTaaog== |
f6710228 Location: |
Summary Statistics: Max. 996.8170809; Mean 407.6235696951276; Valid 3448.0; Min. 70.06522228; StDev 237.51458463418797 Variable Format: numeric Notes: UNF:6:T2v3QX6x3+3lzF5HCLycGg== |
f6710228 Location: |
Summary Statistics: StDev 521.9727937457842; Max. 2382.085262; Mean 637.259498171105; Valid 3448.0; Min. 44.14809988 Variable Format: numeric Notes: UNF:6:OUNPkh673LuQZExMgJTGFA== |
f6710218 Location: |
Summary Statistics: Mean 2003.0; Valid 19.0; StDev 5.627314338711377; Min. 1994.0; Max. 2012.0; Variable Format: numeric Notes: UNF:6:wrIzy4xRVBgA4idzcYYdyQ== |
f6710218 Location: |
Summary Statistics: Max. 2749.0; Valid 19.0; Min. 262.0; StDev 845.9388915206194; Mean 1411.9473684210527 Variable Format: numeric Notes: UNF:6:Gel+7Wz1KYwZfakGQvY5Wg== |
f6710218 Location: |
Summary Statistics: Min. 25.06822058; Mean 37.278471714210525; StDev 8.829428971880557; Max. 55.07038835; Valid 19.0; Variable Format: numeric Notes: UNF:6:Ot+BJ5O0vFQdIgVi5gZp8g== |
Label: |
Abdi_Pfalciparum_replicationVStransmission_readme.txt |
Notes: |
text/plain |
Label: |
All_data_raw_merged.tsv |
Text: |
Metadata, qPCR, Luminex and preprocessed lipidomics data |
Notes: |
text/tsv |
Label: |
forpublication.R |
Notes: |
type/x-r-syntax |