Data for: A multicenter, prospective observational study of intraleukocytic and intraerythrocytic pigment as prognostic features in African children with falciparum malaria (doi:10.7910/DVN/0CTWUJ)

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Data for: A multicenter, prospective observational study of intraleukocytic and intraerythrocytic pigment as prognostic features in African children with falciparum malaria

doi:10.7910/DVN/0CTWUJ

Harvard Dataverse

2020-01-24

2

Olola, Christopher; Agbenyega, Tsiri; Kremsner, Peter Gottfried; Newton, Charles R.; Bojang, Kalifa; Taylor, Terrie, 2020, "Data for: A multicenter, prospective observational study of intraleukocytic and intraerythrocytic pigment as prognostic features in African children with falciparum malaria", https://doi.org/10.7910/DVN/0CTWUJ, Harvard Dataverse, V2

Data for: A multicenter, prospective observational study of intraleukocytic and intraerythrocytic pigment as prognostic features in African children with falciparum malaria

doi:10.7910/DVN/0CTWUJ

Olola, Christopher (Kenya Medical Research Institute for Geographic Medicine, Kilifi, Kenya)

Agbenyega, Tsiri (University of Science and Technology, School of Medical Science, Kumasi, Ghana)

Kremsner, Peter Gottfried (Medical Research Unit, Albert Schweitzer Hospital, Lambaréné; Department of Parasitology, Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany)

Newton, Charles R. (Kenya Medical Research Institute for Geographic Medicine, Kilifi, Kenya)

Bojang, Kalifa (Medical Research Council Laboratories, Banjul, the Gambia)

Taylor, Terrie (College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan; Blantyre Malaria Project, University of Malawi College of Medicine, Blantyre, Malawi)

Harvard Dataverse

Taylor, Terrie

Taylor, Terrie

2020-01-08

https://doi.org/10.7910/DVN/0CTWUJ

Medicine, Health and Life Sciences

<p>This data collection was generated by a study of the prognostic significance of circulating pigment conducted by consortium of research units at five sites (Kenya, Ghana, Gabon, Gambia, Malawi). The study was part of a large multicentre prospective observational study of children admitted with falciparum malaria to SMAC (Severe Malaria in African Children clinical network). The prospective study aimed at setting up a core database to determine prognostic features in African children with severe malaria. It was the first study undertaken by the first clinical network devoted to the study of severe malaria in African children. A detailed description of the study design and participating sites was provided by Taylor T, Olola C, Valim C, et al. Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network. Trans R Soc Trop Med Hyg. 2006;100:615–22 and Olola CH, Missinou MA, Issifou S, et al. Medical informatics in medical research—the Severe Malaria in African Children (SMAC) Network's experience. Methods Inf Med. 2006;45:483–91. </p> <p>From December 2000 through May 2005, all children aged <1 to 180 months who were suspected of having malaria and were sick enough to be hospitalized were screened with a thick blood smear for the presence of P. falciparum parasitemia. Following consent from parents/guardians, children with positive blood smears were recruited into the study. The collection contains data on patient demographics, history of present illness, clinical details at the time of assessment and laboratory investigations. </p>

<strong>Terms of Access </strong> <br> Access to the data file is restricted as it contains sensitive information on participants. For more detailed information beyond the metadata and documentation provided, there is a process of managed access requiring submission of a <a href="http://kemri-wellcome.org/about-us/#ChildVerticalTab_15">request form</a> for consideration by our Data Governance Committee.

Publications based on this data collection should acknowledge this source by means of bibliographic citation.

<p>This data is licensed under the <a href="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</a> <a href="https://creativecommons.org/licenses/by/4.0/legalcode"><img src="https://i.creativecommons.org/l/by/3.0/88x31.png"> </a> </p> For more detailed information beyond the metadata and documentation provided, please contact the author(s) OR the data governance office via this email address: dgc@kemri-wellcome.org

Access to the data file is restricted as it contains sensitive information on participants. For more detailed information beyond the metadata and documentation provided, there is a process of managed access requiring submission of a <a href="http://kemri-wellcome.org/about-us/#ChildVerticalTab_15">request form</a> for consideration by our Data Governance Committee. <ul> <li>No attempt will be made to re-identify respondents, and there will be no use of the identity of any person or establishment discovered inadvertently. Any such discovery will be reported immediately to KEMRI CGMRC. </li> <li>No attempt will be made to produce links between datasets provided in this repository and other datasets that could identify individuals. </li> <li>Any works using this data will cite the source, in line with the citation requirement provided with the dataset.</li> <li>The original collector of the data, KEMRI CGMRC, and the relevant funding agencies bear no responsibility for the data's use or interpretation or inferences based upon it.</li> </ul>

Taylor T, Olola C, Valim C, et al. Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network. Trans R Soc Trop Med Hyg. 2006;100:615–22

10.1016/j.trstmh.2005.09.021

Taylor T, Olola C, Valim C, et al. Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network. Trans R Soc Trop Med Hyg. 2006;100:615–22

Olola CH, Missinou MA, Issifou S, et al. Medical informatics in medical research—the Severe Malaria in African Children (SMAC) Network's experience. Methods Inf Med. 2006;45:483–91.

uuid:edd79265-4e5e-448f-b94b-bd44b5077371

Olola CH, Missinou MA, Issifou S, et al. Medical informatics in medical research—the Severe Malaria in African Children (SMAC) Network's experience. Methods Inf Med. 2006;45:483–91.

Kremsner, Peter Gottfried, et al. "Prognostic value of circulating pigmented cells in African children with malaria." The Journal of infectious diseases 199.1 (2009): 142-150.

10.1086/595295

Kremsner, Peter Gottfried, et al. "Prognostic value of circulating pigmented cells in African children with malaria." The Journal of infectious diseases 199.1 (2009): 142-150.

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SMAC_Pigment Protocol R2001-04-05_NIH V2.pdf

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SMAC_Pigment_Codebook.pdf

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Contains variable description and value labels

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SMAC_Pigment_Codes.txt

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Ethnic Group and Health Centre Codes

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SMAC_Pigment_csv_files.zip

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SMAC_Pigment_Procedure_Manual.pdf

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SMAC_Pigment_Readme.txt

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SMAC_Pigment_surveillance_redacted_CRF.pdf

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