Replication Data for: Antibody responses to crude gametocyte extract predicts P. falciparum gametocyte carriage in Kenya (doi:10.7910/DVN/AUNDEV)

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Part 1: Document Description
Part 2: Study Description
Part 3: Data Files Description
Part 5: Other Study-Related Materials
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Document Description

Citation

Title:

Replication Data for: Antibody responses to crude gametocyte extract predicts P. falciparum gametocyte carriage in Kenya

Identification Number:

doi:10.7910/DVN/AUNDEV

Distributor:

Harvard Dataverse

Date of Distribution:

2020-09-23

Version:

1

Bibliographic Citation:

Omondi, Brian R.; Muthui, Michelle K.; Muasya, William I.; Orindi, Benedict; Mwakubambanya, Ramadhan S.; Bousema, Teun; Drakeley, Chris; Marsh, Kevin; Bejon, Philip; Kapulu, Melissa C., 2020, "Replication Data for: Antibody responses to crude gametocyte extract predicts P. falciparum gametocyte carriage in Kenya", https://doi.org/10.7910/DVN/AUNDEV, Harvard Dataverse, V1, UNF:6:aeC1vJvoAuJvX/RPQrUrDg== [fileUNF]

Study Description

Citation

Title:

Replication Data for: Antibody responses to crude gametocyte extract predicts P. falciparum gametocyte carriage in Kenya

Identification Number:

doi:10.7910/DVN/AUNDEV

Authoring Entity:

Omondi, Brian R. (Department of Biosciences, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Muthui, Michelle K. (Department of Biosciences, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Department of Biochemistry and Molecular Biology, Egerton University, Nakuru, Kenya)

Muasya, William I. (Department of Biosciences, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Orindi, Benedict (Department of Biosciences, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Mwakubambanya, Ramadhan S. (Department of Biochemistry and Molecular Biology, Egerton University, Nakuru, Kenya)

Bousema, Teun (Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, Netherlands)

Drakeley, Chris (Department of Infection Biology, London School of Hygiene & Tropical Medicine, London, UK)

Marsh, Kevin (Department of Biosciences, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK)

Bejon, Philip (Department of Biosciences, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK)

Kapulu, Melissa C. (Department of Biosciences, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK)

Grant Number:

OPP1034789

Grant Number:

092741

Distributor:

Harvard Dataverse

Access Authority:

Kapulu, Melissa C.

Depositor:

Omondi, Brian R.

Date of Deposit:

2020-09-22

Holdings Information:

https://doi.org/10.7910/DVN/AUNDEV

Study Scope

Keywords:

Medicine, Health and Life Sciences

Abstract:

<p>This is a replication dataset for the submitted manuscript titled "<a href="">Antibody responses to crude gametocyte extract predicts P. falciparum gametocyte carriage in Kenya</a>" </p> <p>The dataset constitutes data from two independent cross sectional studies of participants aged 6 months to 67 years. The AFIRM cohort participants were recruited from Junju in Kilifi County and included 413 individuals recruited from January 2014-February 2015. On the other hand, the KMLC cohort included 287 individuals recruited from Junju and Ngerenya in Kilifi County between 1998-2016. Recorded data for each individual includes participant identifier, age, sex, season (AFIRM Cohort) and transmission setting (KMLC Cohort). The parasite density and antibody concentration are provided. </p>

Notes:

<strong>Data Availability</strong> <p>The data are under restricted access, however, are available through the KEMRI-Wellcome Trust Research Programme Data Governance Committee if the use of the data is complaint with the consent provided by the participants. </p> <strong>How to request</strong> <ol> <li>Download and complete the <a href="https://kemri-wellcome.org/wp-content/uploads/2016/02/Data-Sharing-guidelines-External-requests.docx"><strong>data request form</strong></a></li> <li> Email completed data request form to the Data Governance Committee at <a href="mailto:dgc@kemri-wellcome.org?cc=lmwango@kemri-wellcome.org?Subject=Data%20Access%20Request"><strong>dgc@kemri-wellcome.org</strong></a> </li> </ol>

Methodology and Processing

Sources Statement

Data Access

Citation Requirement:

<p>Publications based on this data collection should acknowledge this source by means of bibliographic citation.</p>

Notes:

<p>This data is licensed under the <a href="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</a> <a href="https://creativecommons.org/licenses/by/4.0/legalcode"><img src="https://i.creativecommons.org/l/by/3.0/88x31.png"> </a> </p>

<p>The data are under restricted access, however, are available through the KEMRI-Wellcome Trust Research Programme Data Governance Committee if the use of the data is complaint with the consent provided by the participants. </p> <strong>How to request</strong> <ol> <li>Download and complete the <a href="https://kemri-wellcome.org/wp-content/uploads/2016/02/Data-Sharing-guidelines-External-requests.docx"><strong>data request form</strong></a></li> <li> Email completed data request form to the Data Governance Committee at <a href="mailto:dgc@kemri-wellcome.org?cc=lmwango@kemri-wellcome.org?Subject=Data%20Access%20Request"><strong>dgc@kemri-wellcome.org</strong></a> </li> </ol>

Other Study Description Materials

File Description--f4086510

File: afirm_data.tab

  • Number of cases: 413

  • No. of variables per record: 23

  • Type of File: text/tab-separated-values

Notes:

UNF:6://WKDXMhkGAe57sTfnZOMA==

This file contains the assessment of the infectious reservoir of malaria (AFIRM) study dataset including the participants age, season at recruitment, parasite density and antibody responses. The study was conducted between January 2014 - February 2015 and included 413 participants

File Description--f4086509

File: afirm_kmlc.tab

  • Number of cases: 687

  • No. of variables per record: 13

  • Type of File: text/tab-separated-values

Notes:

UNF:6:Mux8st9RPzy0DrFLkXXS7A==

This file contains data for the combined cohort analysis for both assessment of the infectious reservoir of malaria (AFIRM) and kilifi malaria longitudinal cohort (KMLC). It contains participants age, parasitaemia, antibody reponses of 687 individuals

File Description--f4086508

File: kmlc_data.tab

  • Number of cases: 274

  • No. of variables per record: 21

  • Type of File: text/tab-separated-values

Notes:

UNF:6:F4zzyaf7+YaqHOfXZ2an3A==

This file contains kilifi malaria longitudinal cohort (KMLC) data including participants age, transmission setting, parasite density and antibody responses. The cross-sectional survey was conducted between 1998-2016 and included 274 children aged below 15 years

Other Study-Related Materials

Label:

afirm_correlation.R

Text:

This file contains the R script used for the correlation and comparison analysis in the afirm cohort

Notes:

type/x-r-syntax

Other Study-Related Materials

Label:

afirm_kmlc_combined_correlation.R

Text:

This file contains the R script used for the correlation analysis in the combined cohort analysis (afirm and kmlc)

Notes:

type/x-r-syntax

Other Study-Related Materials

Label:

afirm_kmlc_combined_regression.R

Text:

This file contains the R script used for the logistic regression analysis in the combined cohort (afirm and kmlc)

Notes:

type/x-r-syntax

Other Study-Related Materials

Label:

afirm_regression.R

Text:

This file contains the R script used for the logistic regression analysis in the afirm cohort

Notes:

type/x-r-syntax

Other Study-Related Materials

Label:

Dataset_Codebook_BROmondi.xlsx

Text:

Contains variable descriptions and value labels

Notes:

application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

Other Study-Related Materials

Label:

Data_Readme_BROmondi.txt

Notes:

text/plain

Other Study-Related Materials

Label:

kmlc_correlation.R

Text:

This file contains the R script used for the correlation and comparison analysis in the kmlc cohort

Notes:

type/x-r-syntax

Other Study-Related Materials

Label:

kmlc_regression.R

Text:

This file contains the R script used for the logistic regression analysis in the kmlc cohort

Notes:

type/x-r-syntax