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Part 1: Document Description
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Citation |
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Title: |
First Observation of Experimental Plasmodium vivax Infection of Three Malaria Vectors from the Brazilian Amazon |
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Identification Number: |
doi:10.7910/DVN/DNOHCZ |
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Distributor: |
Harvard Dataverse |
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Date of Distribution: |
2024-03-19 |
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Version: |
1 |
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Bibliographic Citation: |
Araujo, Maisa da Silva; Andrade, Alice Oliveira; Dos Santos, Najara Akir Costa; Castro, Raphael Brum; Pereira, Dhelio Batista; Rodrigues, Moreno Magalhaes de Sourza; Costa, Glaucilene da Silva; Junior, Antonio Marques Pereira; Carvalho, Luis Paulo Costa; Medeiros, Jansen Fenandes de; Pereira-da-Silva, Luiz Hidelbrando, 2024, "First Observation of Experimental Plasmodium vivax Infection of Three Malaria Vectors from the Brazilian Amazon", https://doi.org/10.7910/DVN/DNOHCZ, Harvard Dataverse, V1 |
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Citation |
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Title: |
First Observation of Experimental Plasmodium vivax Infection of Three Malaria Vectors from the Brazilian Amazon |
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Identification Number: |
doi:10.7910/DVN/DNOHCZ |
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Authoring Entity: |
Araujo, Maisa da Silva (Fundação Oswaldo Cruz-Fiocruz Rondônia; Fundação Universidade Federal de Rondônia) |
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Andrade, Alice Oliveira (Fundação Oswaldo Cruz-Fiocruz Rondônia; Fundação Universidade Federal de Rondônia) |
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Dos Santos, Najara Akir Costa (Fundação Oswaldo Cruz-Fiocruz Rondônia; Fundação Universidade Federal de Rondônia) |
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Castro, Raphael Brum (Fundação Oswaldo Cruz-Fiocruz Rondônia) |
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Pereira, Dhelio Batista (Centro de Pesquisa em Medicina Tropical) |
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Rodrigues, Moreno Magalhaes de Sourza (Fundação Oswaldo Cruz-Fiocruz Rondônia) |
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Costa, Glaucilene da Silva (Fundação Oswaldo Cruz-Fiocruz Rondônia; Fundação Universidade Federal de Rondônia) |
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Junior, Antonio Marques Pereira (Fundação Oswaldo Cruz-Fiocruz Rondônia) |
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Carvalho, Luis Paulo Costa (Fundação Oswaldo Cruz-Fiocruz Rondônia; Fundação Universidade Federal de Rondônia) |
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Medeiros, Jansen Fenandes de (Fundação Oswaldo Cruz-Fiocruz Rondônia) |
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Pereira-da-Silva, Luiz Hidelbrando (Instituto de Pesquisas e Patologias Tropicais de Rondônia) |
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Distributor: |
Harvard Dataverse |
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Access Authority: |
Ponmattam, Jamie |
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Depositor: |
Ponmattam, Jamie |
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Date of Deposit: |
2024-03-19 |
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Holdings Information: |
https://doi.org/10.7910/DVN/DNOHCZ |
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Study Scope |
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Keywords: |
Medicine, Health and Life Sciences, Plasmodium vivax, malaria vector, membrane feeding assay, oocysts |
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Abstract: |
Although malaria is endemic to the Amazon region, little is known about the susceptibility of potential parasite vectors in Brazil. Assessing the vector susceptibility of Anopheles mosquitoes will increase our understanding of parasite-vector interactions and aid the design of vector control strategies. This study assessed the susceptibility of three Anopheles species to midgut infection by Plasmodium vivax, the predominant malaria species in Rondônia State, Brazil. Blood from P. vivax infected patients was fed to Anopheles aquasalis, Anopheles darlingi, and Anopheles deaneorum mosquitoes using a membrane feeding assay (MFA). Gametocytemia was estimated by microscopic examination of blood smears and oocyst prevalence, and infection intensity was assessed. The presence of oocysts was determined by microscopy, and the infection rates and infection intensity were determined for all species. Data from six MFAs showed that An. darlingi and An. deaneorum exhibited the highest infection rates (97% and 90%, respectively) and developed a similar median number of P. vivax oocysts (142 and 123, respectively), while An. aquasalis exhibited the smallest infection rates (77%) and the median number of oocysts (88). Established laboratory colonies of An. darlingi and An. deaneorum and susceptibility to plasmodial infection would be beneficial for modeling P. vivax vector-parasite interactions in Brazil. |
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Methodology and Processing |
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Data Access |
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Other Study Description Materials |
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Related Publications |
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Citation |
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Title: |
Araújo MDS, Andrade AO, Dos Santos NAC, Castro RB, Pereira DB, Rodrigues MMS, Costa GDS, Júnior AMP, Carvalho LPC, de Medeiros JF, Pereira-da-Silva LH. First Observation of Experimental Plasmodium vivax Infection of Three Malaria Vectors from the Brazilian Amazon. Vector Borne Zoonotic Dis. 2020 Jul;20(7):517-523. doi: 10.1089/vbz.2019.2527. Epub 2020 Apr 7. PMID: 32255759. |
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Identification Number: |
32255759 |
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Bibliographic Citation: |
Araújo MDS, Andrade AO, Dos Santos NAC, Castro RB, Pereira DB, Rodrigues MMS, Costa GDS, Júnior AMP, Carvalho LPC, de Medeiros JF, Pereira-da-Silva LH. First Observation of Experimental Plasmodium vivax Infection of Three Malaria Vectors from the Brazilian Amazon. Vector Borne Zoonotic Dis. 2020 Jul;20(7):517-523. doi: 10.1089/vbz.2019.2527. Epub 2020 Apr 7. PMID: 32255759. |
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Label: |
PAPER_~1.XLS |
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Notes: |
application/vnd.ms-excel |