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Part 1: Document Description
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Citation |
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Title: |
Replication Data for: Carriage and acquisition of Extended Spectrum Beta-Lactamase producing Enterobacterales among neonates admitted to hospital in Kilifi, Kenya |
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Identification Number: |
doi:10.7910/DVN/E8HR7I |
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Distributor: |
Harvard Dataverse |
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Date of Distribution: |
2020-02-20 |
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Version: |
1 |
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Bibliographic Citation: |
Morpeth, Susan C.; Ngure, Kagia; Scott, J. Anthony G., 2020, "Replication Data for: Carriage and acquisition of Extended Spectrum Beta-Lactamase producing Enterobacterales among neonates admitted to hospital in Kilifi, Kenya", https://doi.org/10.7910/DVN/E8HR7I, Harvard Dataverse, V1, UNF:6:8UZ9sl0WnFQiTiFoxz7pcQ== [fileUNF] |
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Citation |
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Title: |
Replication Data for: Carriage and acquisition of Extended Spectrum Beta-Lactamase producing Enterobacterales among neonates admitted to hospital in Kilifi, Kenya |
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Identification Number: |
doi:10.7910/DVN/E8HR7I |
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Authoring Entity: |
Morpeth, Susan C. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Microbiology Department, Middlemore Hospital, Counties Manukau District Health Board, Private Bag 93311, Otahuhu, Auckland 1640, New Zealand) |
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Ngure, Kagia (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Scott, J. Anthony G. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Other identifications and acknowledgements: |
Michael Ooko |
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Distributor: |
Harvard Dataverse |
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Access Authority: |
Morpeth, Susan C. |
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Depositor: |
Ngure, Kagia |
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Date of Deposit: |
2019-01-22 |
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Holdings Information: |
https://doi.org/10.7910/DVN/E8HR7I |
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Study Scope |
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Keywords: |
Medicine, Health and Life Sciences |
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Abstract: |
<p>Infections caused by extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) among hospitalized neonates in sub-Saharan Africa pose significant clinical challenges. </p> <p>In a cohort study of consecutive neonatal admissions to Kilifi County Hospital (KCH) from July 2013-August 2014, we estimated ESBL-E carriage prevalence on admission using rectal swab cultures and identified risk factors using logistic regression. Swabs were collected at day 0, 2, 4 and 6 and twice-weekly follow up swabs thereafter, we estimated the incidence and identified risk factors for ESBL-E acquisition in hospital using Poisson regression. </p> <p>Data includes admission data for study participants, specimens collected and laboratory results and subsequent data analysis. The prevalence of ESBL-E carriage at admission was 10% (59/569). Caesarean section delivery, older neonatal age, and smaller household size were significant risk factors. Of the 510 infants admitted without ESBL-E carriage, 238 (55%) acquired carriage during their hospital stay. The incidence of acquisition was 21.4% (95% CI 19.0, 24.0) per day. The rate was positively associated with the number of known neonatal ESBL-E carriers and with the total number of neonates on the same ward.</p> |
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Notes: |
Access to the dataset is restricted. Accompanying documentation is available under open access. For more detailed information beyond the metadata and documentation provided, there is a process of managed access requiring submission of a request form for consideration by our Data Governance Committee [dgc@kemri-wellcome.org).<strong> <a href="https://kemri-wellcome.org/wp-content/uploads/2016/02/Data-Sharing-guidelines-External-requests.docx">Click to download Data Request Form</a></strong> |
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Methodology and Processing |
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Sources Statement |
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Data Access |
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Citation Requirement: |
Publications based on this data collection should acknowledge this source by means of bibliographic citation. |
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Notes: |
<p>This data is licensed under the <a href="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</a> <a href="https://creativecommons.org/licenses/by/4.0/legalcode"><img src="https://i.creativecommons.org/l/by/3.0/88x31.png"> </a> </p> For more information on these data, please contact the author(s) via email or the data governance office via this email address: dgc@kemri-wellcome.org |
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Access to the dataset is restricted. Accompanying documentation is available under open access. For more detailed information beyond the metadata and documentation provided, there is a process of managed access requiring submission of a request form for consideration by our Data Governance Committee [dgc@kemri-wellcome.org).<strong> <a href="https://kemri-wellcome.org/wp-content/uploads/2016/02/Data-Sharing-guidelines-External-requests.docx">Click to download Data Request Form</a></strong> |
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Other Study Description Materials |
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File Description--f3346683 |
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File: Neonatal_carriage_analytic_data.tab |
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Notes: |
UNF:6:XJ+KGRVugwvpK6+Zsxej/w== |
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Analytic Dataset - STATA version 15.1 |
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File Description--f3346681 |
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File: Neonatal_carriage_aqcuisition_data.tab |
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Notes: |
UNF:6:caBH+9/8dYGGTbBkYvqaHA== |
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Analytic Dataset - STATA version 15.1 |
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Label: |
Analysis_AST.do |
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Text: |
Analysis Code (STATA version 15.1) |
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Notes: |
application/x-stata-syntax |
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Label: |
Analysis_consenters_non_consenters.do |
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Text: |
Analysis Code (STATA version 15.1) |
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Notes: |
application/x-stata-syntax |
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Label: |
Analysis_Risk_factors_for_acquisition.do |
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Text: |
Analysis Code (STATA version 15.1) |
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Notes: |
application/x-stata-syntax |
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Label: |
Analysis_Risk_factors_for_carriage.do |
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Text: |
Analysis Code (STATA version 15.1) |
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Notes: |
application/x-stata-syntax |
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Label: |
Analysis_Risk_factors_for_carriage_day0.do |
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Text: |
Analysis Code (STATA version 15.1) |
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Notes: |
application/x-stata-syntax |
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Label: |
Ngure_et_al_2018_Codebook.pdf |
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Text: |
Contain variable descriptions, value labels and formats |
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Notes: |
application/pdf |
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Label: |
Ngure_et_al_2018_Data Readme.txt |
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Text: |
Contains summary description of the related research project, dataset, terms of access etc |
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Notes: |
text/plain |