Replication Data for: Temporal trends of SARS-CoV-2 seroprevalence in transfusion blood donors during the first wave of the COVID-19 epidemic in Kenya (doi:10.7910/DVN/FQUNVD)

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Part 1: Document Description
Part 2: Study Description
Part 3: Data Files Description
Part 4: Variable Description
Part 5: Other Study-Related Materials
Entire Codebook

Document Description

Citation

Title:

Replication Data for: Temporal trends of SARS-CoV-2 seroprevalence in transfusion blood donors during the first wave of the COVID-19 epidemic in Kenya

Identification Number:

doi:10.7910/DVN/FQUNVD

Distributor:

Harvard Dataverse

Date of Distribution:

2021-02-08

Version:

1

Bibliographic Citation:

Adetifa, Ifedayo M.O.; Uyoga, Sophie; Gitonga, John N.; Otiende, Mark; Nyagwange, James; Karanja, Henry K.; Tuju, James; Wanjiku, Perpetual; Aman, Rashid; Mwangangi, Mercy; Amoth, Patrick; Kasera, Kadondi; Ng’ang’a, Wangari; Rombo, Charles; Yegon, Christine; Kithi, Khamisi; Odhiambo, Elizabeth; Rotich, Thomas; Orgut, Irene; Kihara, Sammy; Bottomley, Christian; Kagucia, Eunice W.; Gallagher, Katherine E.; Etyang, Anthony; Voller, Shirine; Lambe, Teresa; Wright, Daniel; Barasa, Edwine; Tsofa, Benjamin; Bejon, Philip; Ochola-Oyier, Lynette I.; Agweyu, Ambrose; Scott, J. Anthony G.; Warimwe, George M., 2021, "Replication Data for: Temporal trends of SARS-CoV-2 seroprevalence in transfusion blood donors during the first wave of the COVID-19 epidemic in Kenya", https://doi.org/10.7910/DVN/FQUNVD, Harvard Dataverse, V1, UNF:6:ItlGSwhwfrDEH/48aUySlA== [fileUNF]

Study Description

Citation

Title:

Replication Data for: Temporal trends of SARS-CoV-2 seroprevalence in transfusion blood donors during the first wave of the COVID-19 epidemic in Kenya

Identification Number:

doi:10.7910/DVN/FQUNVD

Authoring Entity:

Adetifa, Ifedayo M.O. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Department of Infectious Diseases Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom)

Uyoga, Sophie (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Gitonga, John N. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Otiende, Mark (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Nyagwange, James (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Karanja, Henry K. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Tuju, James (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Wanjiku, Perpetual (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Aman, Rashid (Ministry of Health, Government of Kenya, Nairobi, Kenya)

Mwangangi, Mercy (Ministry of Health, Government of Kenya, Nairobi, Kenya)

Amoth, Patrick (Ministry of Health, Government of Kenya, Nairobi, Kenya)

Kasera, Kadondi (Ministry of Health, Government of Kenya, Nairobi, Kenya)

Ng’ang’a, Wangari (Presidential Policy & Strategy Unit, The Presidency, Government of Kenya)

Rombo, Charles (Kenya National Blood Transfusion Services, Ministry of Health, Nairobi, Kenya)

Yegon, Christine (Kenya National Blood Transfusion Services, Ministry of Health, Nairobi, Kenya)

Kithi, Khamisi (Kenya National Blood Transfusion Services, Ministry of Health, Nairobi, Kenya)

Odhiambo, Elizabeth (Kenya National Blood Transfusion Services, Ministry of Health, Nairobi, Kenya)

Rotich, Thomas (Kenya National Blood Transfusion Services, Ministry of Health, Nairobi, Kenya)

Orgut, Irene (Kenya National Blood Transfusion Services, Ministry of Health, Nairobi, Kenya)

Kihara, Sammy (Kenya National Blood Transfusion Services, Ministry of Health, Nairobi, Kenya)

Bottomley, Christian (Department of Infectious Diseases Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom)

Kagucia, Eunice W. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Gallagher, Katherine E. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Department of Infectious Diseases Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom)

Etyang, Anthony (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Voller, Shirine (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Department of Infectious Diseases Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom)

Lambe, Teresa (Nuffield Department of Medicine, Oxford University, United Kingdom)

Wright, Daniel (Nuffield Department of Medicine, Oxford University, United Kingdom)

Barasa, Edwine (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Tsofa, Benjamin (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Bejon, Philip (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Nuffield Department of Medicine, Oxford University, United Kingdom)

Ochola-Oyier, Lynette I. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Agweyu, Ambrose (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Scott, J. Anthony G. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Department of Infectious Diseases Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom; Nuffield Department of Medicine, Oxford University, United Kingdom)

Warimwe, George M. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Nuffield Department of Medicine, Oxford University, United Kingdom)

Distributor:

Harvard Dataverse

Access Authority:

Adetifa, Ifedayo M.O.

Access Authority:

Uyoga, Sophie

Depositor:

Adetifa, Ifedayo M.O.

Date of Deposit:

2021-02-08

Study Scope

Keywords:

Medicine, Health and Life Sciences, COVID-19, SARS-CoV-2, Sero-epidemiology

Abstract:

<p>This is a replication dataset for the manuscriot titled: "<a href="">Temporal trends of SARS-CoV-2 seroprevalence in transfusion blood donors during the first wave of the COVID-19 epidemic in Kenya</a>". </p> <p>These data contain anonymised residual donor serum samples used for screening of transfusion transmissible infections were collected at the KNBTS regional centres in 4 sites (Mombasa, Nairobi, Eldoret and Kisumu) which has been used to compute standardised prevalence by age, sex and region using KNBS population as the standard population.</p>

Notes:

<strong>Data Availability</strong> <p>Access to these data requires submission of a formal request for consideration by our Data Governance Committee. </p> <strong>How to request</strong> <ol> <li>Download and complete the <a href="https://kemri-wellcome.org/wp-content/uploads/2016/02/Data-Sharing-guidelines-External-requests.docx"><strong>data request form</strong></a></li> <li> Email completed data request form to the Data Governance Committee at <a href="mailto:dgc@kemri-wellcome.org?cc=lmwango@kemri-wellcome.org?Subject=Data%20Access%20Request"><strong>dgc@kemri-wellcome.org</strong></a> </li> </ol>

Methodology and Processing

Sources Statement

Data Access

Citation Requirement:

<p>Publications based on this data collection should acknowledge this source by means of bibliographic citation.</p>

Notes:

<p>This data is licensed under the <a href="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</a> <a href="https://creativecommons.org/licenses/by/4.0/legalcode"><img src="https://i.creativecommons.org/l/by/3.0/88x31.png"> </a> </p>

Access to the dataset is restricted. Accompanying documentation is available under open access. For more detailed information beyond the metadata and documentation provided, there is a process of managed access requiring submission of a request form for consideration by our Data Governance Committee [dgc@kemri-wellcome.org].<strong> <a href="https://kemri-wellcome.org/wp-content/uploads/2016/02/Data-Sharing-guidelines-External-requests.docx">Click to download Data Request Form</a></strong>

Other Study Description Materials

File Description--f4372958

File: 2021-01-11_knbts_data.tab

  • Number of cases: 9922

  • No. of variables per record: 9

  • Type of File: text/tab-separated-values

Notes:

UNF:6:nr4PLdhgftlPltZpxDf8KQ==

File Description--f4372962

File: clean_individual_level_data_2021-01-10.tab

  • Number of cases: 9922

  • No. of variables per record: 16

  • Type of File: text/tab-separated-values

Notes:

UNF:6:sfAAO4kZH9epmxXuxhB3GA==

File Description--f4372961

File: clean_individual_level_data_2021-01-10.tab

  • Number of cases: 9922

  • No. of variables per record: 16

  • Type of File: text/tab-separated-values

Notes:

UNF:6:1+imDPSsuDANocYLjxqlsQ==

File Description--f4372963

File: KNBS_Census_2019_Age_Sex_County.tab

  • Number of cases: 4747

  • No. of variables per record: 5

  • Type of File: text/tab-separated-values

Notes:

UNF:6:r2+wX5d88nSlP1/nWjJVtA==

File Description--f4372957

File: KNBS_Census_2019_Age_Sex_County.tab

  • Number of cases: 4747

  • No. of variables per record: 5

  • Type of File: text/tab-separated-values

Notes:

UNF:6:C1NSKEVBEfBTxhbn/9SsYg==

Variable Description

List of Variables:

Variables

region

f4372958 Location:

Summary Statistics: Valid 9922.0; StDev 2.0711849957144026; Min. 1.0; Mean 4.44033460995773; Max. 8.0;

Variable Format: numeric

Notes: UNF:6:GLtafhcG6cOlfe4tqckvCA==

agecat

f4372958 Location:

Summary Statistics: Valid 9922.0; Mean 2.1705301350534083; Min. 1.0; Max. 5.0; StDev 0.990299844505186

Variable Format: numeric

Notes: UNF:6:cQ0c/+1sppW3aXEPoC/MOQ==

sex

f4372958 Location:

Summary Statistics: Mean 1.8082039911308194; Valid 9922.0; Min. 1.0; Max. 2.0; StDev 0.3937333162361006;

Variable Format: numeric

Notes: UNF:6:A+k4KleJgAaGU91rHHqFJA==

pop

f4372958 Location:

Summary Statistics: Max. 1300000.0; StDev 341910.0732092176; Min. 17586.0; Mean 473949.08637373295; Valid 9922.0

Variable Format: numeric

Notes: UNF:6:+TfGjII6X2+TlRXt/Kl3jw==

pw

f4372958 Location:

Summary Statistics: StDev 0.012814562492774184; Mean 0.017547928189880973; Min. 6.477E-4; Max. 0.0493087; Valid 9922.0;

Variable Format: numeric

Notes: UNF:6:EcpHwq4w081lXGKYv+SkKQ==

period3

f4372958 Location:

Summary Statistics: Max. 3.0; Min. 1.0; Valid 9922.0; StDev 0.8442853816788196; Mean 2.0363837935899993;

Variable Format: numeric

Notes: UNF:6:UVlvq5NWzAQgphdYtSsd0Q==

period10

f4372958 Location:

Summary Statistics: Max. 10.0; StDev 2.7425295587641507; Min. 1.0; Mean 5.773835920177393; Valid 9922.0

Variable Format: numeric

Notes: UNF:6:25vsr+EWj0DM+bhHK+LZDQ==

collect_date

f4372958 Location:

Variable Format: character

Notes: UNF:6:8cnZtgfE9U7BG06yMiDZGA==

spikepos

f4372958 Location:

Summary Statistics: Max. 1.0; StDev 0.2911877452405886; Mean 0.09352953033662646; Valid 9922.0; Min. 0.0

Variable Format: numeric

Notes: UNF:6:qsdU7SyWivmY1cwgrPdSzA==

sample_id

f4372962 Location:

Variable Format: character

Notes: UNF:6:/bqPYbtcehEuJoALI192rQ==

collect_date

f4372962 Location:

Variable Format: character

Notes: UNF:6:AM2RywnNzAtVuJ6tFzfkUg==

age_yr

f4372962 Location:

Summary Statistics: Max. 64.0; Valid 9922.0; StDev 9.36411650017372; Mean 31.222334206813088; Min. 15.0

Variable Format: numeric

Notes: UNF:6:+9TnL5hpIJMw0pWVwZXaSg==

spikeod

f4372962 Location:

Summary Statistics: StDev 0.273078821988565; Mean 0.19325176372404743; Max. 3.8299999; Min. 0.048; Valid 9922.0;

Variable Format: numeric

Notes: UNF:6:Hs/ty9X0r1wYWHGFiugqWA==

spike_negod

f4372962 Location:

Summary Statistics: Mean 0.14038913525498906; Max. 0.189; StDev 0.019564764680732656; Min. 0.108; Valid 9922.0

Variable Format: numeric

Notes: UNF:6:Zdt5k1mYp8WxrSIE8Ak0/g==

spikeratio

f4372962 Location:

Summary Statistics: Max. 30.8871; Valid 9922.0; Min. 0.283; Mean 1.3745853785325541; StDev 1.9021173348553915

Variable Format: numeric

Notes: UNF:6:OYFcY8dFkLKD7fzbA9hW6A==

spikepos

f4372962 Location:

Summary Statistics: Mean 0.09352953033662323; StDev 0.291187745240587; Min. 0.0; Max. 1.0; Valid 9922.0;

Variable Format: numeric

Notes: UNF:6:5EQGYSF5k7hSNVOOad2ELA==

rbtc

f4372962 Location:

Variable Format: character

Notes: UNF:6:DzE44gysrDKncryg5b+HnQ==

county

f4372962 Location:

Variable Format: character

Notes: UNF:6:VwFYd5W8koKjrXb0r5YGkA==

vnrd

f4372962 Location:

Variable Format: character

Notes: UNF:6:XOjfj4W24Uwn24j/aRSNpw==

batch

f4372962 Location:

Summary Statistics: Mean 1.6877645635960121; StDev 0.4634286504991575; Min. 1.0; Max. 2.0; Valid 9922.0

Variable Format: numeric

Notes: UNF:6:MCfwn7h1JEDUU9T3B5YBqQ==

sex

f4372962 Location:

Variable Format: character

Notes: UNF:6:Zrm3oK9osDn3kKpDIinSew==

province

f4372962 Location:

Variable Format: character

Notes: UNF:6:I4QWG4d2Vb5rFICBaGP6PQ==

age_category

f4372962 Location:

Variable Format: character

Notes: UNF:6:hs4Tm5wEBf1SAH38Md3JJA==

period3

f4372962 Location:

Summary Statistics: Min. 1.0; StDev 0.8442853816789069; Valid 9922.0; Max. 3.0; Mean 2.036383793589941

Variable Format: numeric

Notes: UNF:6:i28OeDEkaH59KxYMMWIu4w==

period10

f4372962 Location:

Summary Statistics: Max. 10.0; Mean 5.773835920177221; StDev 2.742529558764224; Min. 1.0; Valid 9922.0

Variable Format: numeric

Notes: UNF:6:aNytJBEUpxhN44vme8CEQQ==

unique identifier of the sample

f4372961 Location:

Variable Format: character

Notes: UNF:6:/bqPYbtcehEuJoALI192rQ==

date of sample collection

f4372961 Location:

Variable Format: character

Notes: UNF:6:NP79t90lMVdeIExzQ1Fm0w==

age in years

f4372961 Location:

Summary Statistics: Min. 15.0; Max. 64.0; StDev 9.36411650017372; Valid 9922.0; Mean 31.222334206813088;

Variable Format: numeric

Notes: UNF:6:+9TnL5hpIJMw0pWVwZXaSg==

spikeod

f4372961 Location:

Summary Statistics: Valid 9922.0; Min. 0.04800000041723251; Max. 3.8299999237060547; Mean 0.1932517638568366; StDev 0.27307882223132524

Variable Format: numeric

Notes: UNF:6:Hs/ty9X0r1wYWHGFiugqWA==

spike_negod

f4372961 Location:

Summary Statistics: Valid 9922.0; Max. 0.1889999955892563; Min. 0.1080000028014183; Mean 0.1403891347995562; StDev 0.019564764722199462

Variable Format: numeric

Notes: UNF:6:Zdt5k1mYp8WxrSIE8Ak0/g==

spikeratio

f4372961 Location:

Summary Statistics: Min. 0.28299999237060547; Valid 9922.0; StDev 1.902117329328536; Max. 30.887096405029297; Mean 1.3745853753147221

Variable Format: numeric

Notes: UNF:6:uWWdunG+hBOaeaknAtNMaw==

SARS-CoV-2 antibody status: 1=positive; 0=negative

f4372961 Location:

Summary Statistics: Mean 0.09352953033662323; StDev 0.291187745240587; Min. 0.0; Max. 1.0; Valid 9922.0

Variable Format: numeric

Notes: UNF:6:5EQGYSF5k7hSNVOOad2ELA==

Regional Blood Transfusion Center

f4372961 Location:

Variable Format: character

Notes: UNF:6:DzE44gysrDKncryg5b+HnQ==

county - 31 out of all the 47

f4372961 Location:

Variable Format: character

Notes: UNF:6:VwFYd5W8koKjrXb0r5YGkA==

voluntary non-remunerated blood donors

f4372961 Location:

Value

Label

Frequency

Text

0.

Family_replacement_donor

9632

1.

Voluntary_donor

290

Summary Statistics: Valid 9922.0; Min. 0.0; Max. 1.0; Mean 0.029227978230197342; StDev 0.1684534460402456

Variable Format: numeric

Notes: UNF:6:LI+ix8IpuuZlHpc0US9/Jg==

data batch - first batch was 3156 and second one is 7042

f4372961 Location:

Summary Statistics: StDev 0.4634286504991575; Max. 2.0; Min. 1.0; Valid 9922.0; Mean 1.6877645635960121

Variable Format: numeric

Notes: UNF:6:MCfwn7h1JEDUU9T3B5YBqQ==

sex

f4372961 Location:

Value

Label

Frequency

Text

1.

female

1903

2.

male

8019

Summary Statistics: Max. 2.0; StDev 0.3937333162360972; Min. 1.0; Mean 1.808203991130821; Valid 9922.0;

Variable Format: numeric

Notes: UNF:6:bUzVlUx3yBLU9JstJ4jARg==

former administrative units in Kenya

f4372961 Location:

Variable Format: character

Notes: UNF:6:I4QWG4d2Vb5rFICBaGP6PQ==

RECODE of age_yr (age in years)

f4372961 Location:

Value

Label

Frequency

Text

4.

45-54yrs

794

3.

35-44yrs

2261

1.

15-24yrs

2763

5.

55-64yrs

202

2.

25-34yrs

3902

Summary Statistics: Valid 9922.0; Max. 5.0; Min. 1.0; Mean 2.1705301350534207; StDev 0.9902998445051721

Variable Format: numeric

Notes: UNF:6:Y3NIURtKLUBM7ooMz3DaDA==

period3

f4372961 Location:

Summary Statistics: StDev 0.8442853816789069; Valid 9922.0; Max. 3.0; Mean 2.036383793589941; Min. 1.0

Variable Format: numeric

Notes: UNF:6:i28OeDEkaH59KxYMMWIu4w==

period10

f4372961 Location:

Summary Statistics: Min. 1.0; Max. 10.0; Mean 5.773835920177221; Valid 9922.0; StDev 2.742529558764224

Variable Format: numeric

Notes: UNF:6:aNytJBEUpxhN44vme8CEQQ==

age_yr

f4372963 Location:

Summary Statistics: Valid 4747.0; Min. 0.0; Mean 50.0; StDev 29.157830821032412; Max. 100.0;

Variable Format: numeric

Notes: UNF:6:2kdhy71MujkuZybiY7fcIQ==

male

f4372963 Location:

Summary Statistics: StDev 6788.8914549215815; Valid 4747.0; Min. 2.0; Mean 4960.537392037142; Max. 64070.0

Variable Format: numeric

Notes: UNF:6:RV3zzZGq7udcgN5gCXpjOw==

female

f4372963 Location:

Summary Statistics: Valid 4747.0; Min. 2.0; Max. 70152.0; Mean 5058.862228776113; StDev 6904.475478144375;

Variable Format: numeric

Notes: UNF:6:Fg8t7JP0OuIfHuXPqQ7X1w==

total

f4372963 Location:

Summary Statistics: Valid 4747.0; Mean 10019.39962081301; StDev 13664.530092712286; Min. 4.0; Max. 133373.0

Variable Format: numeric

Notes: UNF:6:VGA0MBR9KY53VBWNyIkTDg==

county

f4372963 Location:

Variable Format: character

Notes: UNF:6:Ah0tV++a+RMImL8vBE8zcQ==

age_yr

f4372957 Location:

Variable Format: character

Notes: UNF:6:42Bz3IChAAji8YE9GNnj5A==

male

f4372957 Location:

Summary Statistics: Min. 2.0; Max. 64070.0; StDev 6788.8914549215815; Mean 4960.537392037142; Valid 4747.0;

Variable Format: numeric

Notes: UNF:6:RV3zzZGq7udcgN5gCXpjOw==

female

f4372957 Location:

Summary Statistics: Mean 5058.862228776113; Valid 4747.0; Min. 2.0; Max. 70152.0; StDev 6904.475478144375;

Variable Format: numeric

Notes: UNF:6:Fg8t7JP0OuIfHuXPqQ7X1w==

total

f4372957 Location:

Summary Statistics: StDev 13664.530092712286; Valid 4747.0; Min. 4.0; Max. 133373.0; Mean 10019.39962081301;

Variable Format: numeric

Notes: UNF:6:VGA0MBR9KY53VBWNyIkTDg==

county

f4372957 Location:

Variable Format: character

Notes: UNF:6:Ah0tV++a+RMImL8vBE8zcQ==

Other Study-Related Materials

Label:

1.1_structuring_&_QC.do

Notes:

application/x-stata-syntax

Other Study-Related Materials

Label:

2.0_national_prevalence_age_sex_adjusted.do

Text:

for computing the age-sex adjusted national prevalence estimate

Notes:

application/x-stata-syntax

Other Study-Related Materials

Label:

4.0_province_prevalence_age_sex_adjusted.do

Text:

for computing the age-sex adjusted prevalence for each province

Notes:

application/x-stata-syntax

Other Study-Related Materials

Label:

IAdetifa_Blood_Donors_Seroprevalence_Data_Codebook.pdf

Notes:

application/pdf

Other Study-Related Materials

Label:

IAdetifa_Blood_Donors_Seroprevalence_Data_Readme.TXT

Notes:

text/plain

Other Study-Related Materials

Label:

KNBTS_dec_analysis_version 3.Rmd

Text:

for Bayesian multilevel regression and post-stratification to account for non-random sampling with respect to age, sex and province, adjusted for assay performance

Notes:

application/octet-stream