Data for: Comparison of methods for measuring blood lactate and blood gases (doi:10.7910/DVN/GLHP4D)

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Part 1: Document Description
Part 2: Study Description
Part 3: Data Files Description
Part 4: Variable Description
Part 5: Other Study-Related Materials
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Document Description

Citation

Title:

Data for: Comparison of methods for measuring blood lactate and blood gases

Identification Number:

doi:10.7910/DVN/GLHP4D

Distributor:

Harvard Dataverse

Date of Distribution:

2020-02-17

Version:

1

Bibliographic Citation:

Olola, Christopher; Lowe, Brett; Krishna, Sanjeev; Agbenyega, Tsiri; Newton, Charles R.; Wypij, David; Taylor, Terrie, 2020, "Data for: Comparison of methods for measuring blood lactate and blood gases", https://doi.org/10.7910/DVN/GLHP4D, Harvard Dataverse, V1, UNF:6:K2yHeC+EXRCSdRfJc9W7lg== [fileUNF]

Study Description

Citation

Title:

Data for: Comparison of methods for measuring blood lactate and blood gases

Identification Number:

doi:10.7910/DVN/GLHP4D

Authoring Entity:

Olola, Christopher (KEMRI Centre for Geographic Medicine Research (Coast), Kilifi, Kenya)

Lowe, Brett (KEMRI Centre for Geographic Medicine Research (Coast), Kilifi, Kenya)

Krishna, Sanjeev (St. George’s Hospital Medical School, London, UK)

Agbenyega, Tsiri (University of Science and Technology, School of Medical Science, Kumasi, Ghana)

Newton, Charles R. (KEMRI Centre for Geographic Medicine Research (Coast), Kilifi, Kenya)

Wypij, David (Harvard School of Public Health, Clinical Research Program, Boston, USA)

Taylor, Terrie (Blantyre Malaria Project, University of Malawi College of Medicine, Blantyre, Malawi)

Distributor:

Harvard Dataverse

Access Authority:

Olola, Christopher

Access Authority:

Taylor, Terrie

Depositor:

Taylor, Terrie

Date of Deposit:

2020-02-03

Holdings Information:

https://doi.org/10.7910/DVN/GLHP4D

Study Scope

Keywords:

Medicine, Health and Life Sciences

Abstract:

<p>This dataset was generated by a sub-study of a prospective observational study of children admitted with falciparum malaria to Kilifi District Hospital as part of a core database to determine prognostic features in African children. In the main study, the prognostic significance of malarial pigment (in red cells, and in white cells), together with other laboratory and clinical parameters are being determined (<a href="https://doi.org/10.1016/j.trstmh.2005.09.021"> doi: 10.1016/j.trstmh.2005.09.021</a>). </p> <p>The purpose of the study was to compare the current SMAC methods for measuring acid/base status (the pHOx machine) and whole blood lactate concentrations (Lactate Pro) with the standard methods previously used in two sites. The data generated was considered in deciding which methods should be recommended for all SMAC sites. The Severe Malaria in African Children (SMAC) network’s site in Kenya was the only site routinely measuring acid/base status prior to the pigment study, and this site had been using the Instrumentation Laboratory 1620 blood gas analyzer to assess acid/base status. The SMAC site in Kenya had been using the Analox GM7 machine (Analox Instruments Ltd., London, UK) for its lactate measurements, and the Ghanaian site had been using the YSI 2300 analyzer (YSI Incorporated/YSI Life Sciences, Hampshire, England) for its lactate measurements. In a pilot study, agreement between the Lactate Pro and the YSI 2300 in Ghana was very good, but agreement between the Lactate Pro and the Analox GM7 in Kenya was poor. To eliminate site-to-site variability, one of the YSI 2300 machines from Ghana has been shipped to Kenya so that a direct comparison between the YSI 2300 and the Analox GM7 can be made in Kenya </p> <p>Comparisons were made between two different Lactate Pro machines, between test strips from two different lots in the two different Lactate Pro machines, between the Lactate Pro analyzers, and between the Lactate Pro analyzers and two reference standards in Kenya. </p>

Kind of Data:

Laboratory methods data

Methodology and Processing

Sources Statement

Data Access

Citation Requirement:

Publications based on this data collection should acknowledge this source by means of bibliographic citation.

Notes:

<p>This data is licensed under the <a href="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</a> <a href="https://creativecommons.org/licenses/by/4.0/legalcode"><img src="https://i.creativecommons.org/l/by/3.0/88x31.png"> </a> </p>

Data and documentation are openly available. For more detailed information beyond the metadata and documentation provided, please contact the author(s) OR the data governance office via this email address: dgc@kemri-wellcome.org <ul> <li>No attempt will be made to re-identify respondents, and there will be no use of the identity of any person or establishment discovered inadvertently. Any such discovery will be reported immediately to KEMRI CGMRC. </li> <li>No attempt will be made to produce links between datasets provided in this repository and other datasets that could identify individuals. </li> <li>Any works using this data will cite the source, in line with the citation requirement provided with the dataset.</li> <li>The original collector of the data, KEMRI CGMRC, and the relevant funding agencies bear no responsibility for the data's use or interpretation or inferences based upon it.</li> </ul>

Other Study Description Materials

Related Studies

Olola, Christopher; Agbenyega, Tsiri; Kremsner, Peter Gottfried; Newton, Charles R.; Bojang, Kalifa; Taylor, Terrie, 2020, "Data for: A multicenter, prospective observational study of intraleukocytic and intraerythrocytic pigment as prognostic features in African children with falciparum malaria", https://doi.org/10.7910/DVN/0CTWUJ, Harvard Dataverse, V1

File Description--f3676739

File: Ghana_Lactate.tab

  • Number of cases: 320

  • No. of variables per record: 6

  • Type of File: text/tab-separated-values

Notes:

UNF:6:fFRpi9pAlLc7TD8ohfjUCQ==

De-identified raw data

File Description--f3676740

File: Kenya_Lactate.tab

  • Number of cases: 345

  • No. of variables per record: 6

  • Type of File: text/tab-separated-values

Notes:

UNF:6:WJSFLygx9rF8JYszhAJZdw==

De-identified raw data

Variable Description

List of Variables:

Variables

Paxno

f3676739 Location:

Summary Statistics: StDev 92.52026804976302; Min. 1.0; Valid 320.0; Max. 320.0; Mean 160.5

Variable Format: numeric

Notes: UNF:6:vtZ3/+FswcpKe6VRHsnuDg==

Lact1A

f3676739 Location:

Summary Statistics: Valid 320.0; Mean 4.8928125; StDev 3.674095316001726; Min. 1.0; Max. 17.9

Variable Format: numeric

Notes: UNF:6:AQ1xwy2HVbVQF+5ACklWCA==

Lact1B

f3676739 Location:

Summary Statistics: Valid 320.0; StDev 3.6375259750874265; Min. 0.9; Max. 16.9; Mean 4.941875

Variable Format: numeric

Notes: UNF:6:TbS6cvTvnQHXgtF+D9sYLA==

Lact2A

f3676739 Location:

Summary Statistics: Min. 0.9; StDev 3.651099146888171; Max. 17.2; Mean 4.8871875000000005; Valid 320.0;

Variable Format: numeric

Notes: UNF:6:mDwwEEQypXBGt7zyF+yKDA==

Lact2B

f3676739 Location:

Summary Statistics: Valid 320.0; Max. 17.2; StDev 3.637095322155461; Mean 4.92625; Min. 0.9

Variable Format: numeric

Notes: UNF:6:LK3dD1XNSd4FogWsZv4x4w==

YSI

f3676739 Location:

Summary Statistics: StDev 3.19056355943625; Min. 0.7; Max. 21.1; Valid 320.0; Mean 3.8953125

Variable Format: numeric

Notes: UNF:6:Rdl9Blc/2HUxJOdvgodJJQ==

SERIALNO

f3676740 Location:

Summary Statistics: Mean 17300.0; Min. 100.0; StDev 9973.715456137697; Valid 345.0; Max. 34500.0;

Variable Format: numeric

Notes: UNF:6:Re8xJ8zCC8USnYl5hpdPBg==

DATE

f3676740 Location:

Summary Statistics: StDev 0.0; Max. 2002.0; Min. 2002.0; Mean 2002.0; Valid 345.0;

Variable Format: numeric

Notes: UNF:6:QH62lH6oefDy7fMG4c9QkA==

YSI

f3676740 Location:

Summary Statistics: StDev 2.7336271283242866; Valid 345.0; Mean 5.213072463768116; Max. 26.0; Min. 1.26

Variable Format: numeric

Notes: UNF:6:k4svhdrf0sVOzj4sjn+4ag==

LACTATEPRO1

f3676740 Location:

Summary Statistics: StDev 2.4582337586158602; Valid 345.0; Min. 0.9; Max. 13.0; Mean 4.891014492753623

Variable Format: numeric

Notes: UNF:6:Pe5MLs9i9D/d/5Bnsh/gAQ==

LACTATEPRO2

f3676740 Location:

Summary Statistics: Valid 345.0; Max. 12.4; StDev 2.4713497183525206; Min. 1.0; Mean 4.912753623188406

Variable Format: numeric

Notes: UNF:6:byspikdTzqdc5OWN4rhtyw==

GM7

f3676740 Location:

Summary Statistics: StDev 2.6233276569722466; Max. 22.5; Mean 3.8147058823529414; Valid 340.0; Min. 0.6

Variable Format: numeric

Notes: UNF:6:A+sDJCuSiY5Px63IAMJGjQ==

Other Study-Related Materials

Label:

SMAC_LactatePro_Codebook.pdf

Text:

Data Dictionary containing variable description and value labels

Notes:

application/pdf

Other Study-Related Materials

Label:

SMAC_LatactePro_Protocol R2002-02-11.pdf

Text:

Study Protocol

Notes:

application/pdf