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Part 1: Document Description
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Citation |
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Title: |
Replication Data for: Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro |
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Identification Number: |
doi:10.7910/DVN/LBSUYU |
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Distributor: |
Harvard Dataverse |
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Date of Distribution: |
2024-06-03 |
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Version: |
2 |
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Bibliographic Citation: |
Nyagwange, James; Kutima, Bernadette; Mwai, Kennedy, 2024, "Replication Data for: Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro", https://doi.org/10.7910/DVN/LBSUYU, Harvard Dataverse, V2 |
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Citation |
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Title: |
Replication Data for: Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro |
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Identification Number: |
doi:10.7910/DVN/LBSUYU |
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Authoring Entity: |
Nyagwange, James (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Kutima, Bernadette (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Mwai, Kennedy (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Distributor: |
Harvard Dataverse |
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Access Authority: |
Nyagwange, James |
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Access Authority: |
The Data Governance Committee |
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Depositor: |
Nyagwange, James |
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Date of Deposit: |
2024-05-28 |
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Holdings Information: |
https://doi.org/10.7910/DVN/LBSUYU |
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Study Scope |
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Keywords: |
Medicine, Health and Life Sciences, SARS-CoV-2, Human coronaviruses, Pre-existing antibodies, Spike proteins |
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Abstract: |
<p>This is a replication dataset for the publication titled: "<strong><i>Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro</i></strong>."</p> <p>The dataset used in this study included serum samples collected in 2018 in coastal Kenya from adults for malaria cross-sectional surveys, serum samples collected in 2020 Kenya-wide from adults investigated for SARS-CoV-2 infection.The prepandemic NP/OP samples were obtained from biobanked human NP/OP samples collected from study participants between 2015 and 2017 in the Kilifi Health and Demographic Surveillance System. The pandemic NP/OP samples set were SARS-CoV-2 RT-PCR test samples performed at the KEMRI-CGMRC between March and July 2020. Both sera and NP/OP before and during the COVID-19 pandemic provided the basis for comparison of immune responses between the two periods. </p> |
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Kind of Data: |
Restricted Access |
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Notes: |
<strong>Data Availability</strong> <p>Access to these data requires submission of a formal request for consideration by our Data Governance Committee. </p> <strong>How to request</strong> <ol> <li>Download and complete the <a href="https://kemri-wellcome.org/zp-content/uploads/2021/02/KWTRP_Dataverse_Data_Request_Form_2019.docx"><strong>data request form</strong></a></li> <li> Email completed data request form to the Data Governance Committee at <a href="mailto:dgc@kemri-wellcome.org?cc=lmwango@kemri-wellcome.org?Subject=Data%20Access%20Request"><strong>dgc@kemri-wellcome.org</strong></a> </li> </ol> |
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Methodology and Processing |
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Sources Statement |
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Data Access |
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Notes: |
For more detailed information beyond the metadata and documentation provided, there is a process of managed access requiring submission of a request form for consideration by our Data Governance Committee [dgc@kemri-wellcome.org].<strong> <a href="https://kemri-wellcome.org/zp-content/uploads/2021/02/KWTRP_Dataverse_Data_Request_Form_2019.docx">Click to download Data Request Form</a></strong> |
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Other Study Description Materials |
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Related Publications |
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Citation |
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Title: |
Nyagwange, J., Kutima, B., Mwai, K., Karanja, H.K., Gitonga, J.N., Mugo, D., Sein, Y., Wright, D., Omuoyo, D.O., Nyiro, J.U. and Tuju, J., 2023. Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro. International Journal of Infectious Diseases, 127, pp.11-16. |
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Identification Number: |
10.1016/j.ijid.2022.11.041 |
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Bibliographic Citation: |
Nyagwange, J., Kutima, B., Mwai, K., Karanja, H.K., Gitonga, J.N., Mugo, D., Sein, Y., Wright, D., Omuoyo, D.O., Nyiro, J.U. and Tuju, J., 2023. Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro. International Journal of Infectious Diseases, 127, pp.11-16. |
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Label: |
code.zip |
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Notes: |
application/zip |
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Label: |
data.zip |
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Notes: |
application/zip |
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Label: |
functions.R |
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Notes: |
type/x-r-syntax |
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Label: |
Nyagwange_Serum IgG_Data_Readme.txt |
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Notes: |
text/plain |