Effects of Vitamin D Supplementation on Testosterone, Prostate, and Lower Urinary Tract Symptoms: A Prospective, Comparative Study (doi:10.7910/DVN/NAL4HW)

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Document Description

Citation

Title:

Effects of Vitamin D Supplementation on Testosterone, Prostate, and Lower Urinary Tract Symptoms: A Prospective, Comparative Study

Identification Number:

doi:10.7910/DVN/NAL4HW

Distributor:

Harvard Dataverse

Date of Distribution:

2023-01-02

Version:

1

Bibliographic Citation:

Min Gu Park, 2023, "Effects of Vitamin D Supplementation on Testosterone, Prostate, and Lower Urinary Tract Symptoms: A Prospective, Comparative Study", https://doi.org/10.7910/DVN/NAL4HW, Harvard Dataverse, V1

Study Description

Citation

Title:

Effects of Vitamin D Supplementation on Testosterone, Prostate, and Lower Urinary Tract Symptoms: A Prospective, Comparative Study

Identification Number:

doi:10.7910/DVN/NAL4HW

Authoring Entity:

Min Gu Park (Department of Urology, Inje University Seoul Paik Hospital, Inje University College of Medicine)

Distributor:

Harvard Dataverse

Access Authority:

Park, Hyun Jun

Depositor:

Park, Hyun Jun

Date of Deposit:

2023-01-02

Holdings Information:

https://doi.org/10.7910/DVN/NAL4HW

Study Scope

Keywords:

Medicine, Health and Life Sciences

Abstract:

Purpose: Several studies have associated the serum vitamin D level with total testosterone levels and the prostate volume. Herein, we investigated the effect of vitamin D supplementation on testosterone, prostate, and lower urinary tract symptoms (LUTS) in men. Materials and Methods: Men over 40 years of age diagnosed with a vitamin D deficiency (25[OH]D <20 ng/mL) who received vitamin D supplementation for one year were included in the study and administered 25,000 IU of cholecalciferol every 2 weeks. Prostate ultrasound, uroflowmetry, postvoid residual urine volume measurement, and serological tests (serum testosterone levels, etc.) were performed upon diagnosis and one year later. Participants also answered the International Prostate Symptom Score (IPSS) and Aging Males’ Symptoms Scale (AMS) questionnaires. Results: A significant increase was observed in the vitamin D level following one year of vitamin D supple-mentation, with a significant decrease in the postvoid residual urine volume, total IPSS score and without a significant change in the prostate volume. Improved psychological subscale score of AMS questionnaire was observed with a statistical significance. Conclusions: Vitamin D supplementation suppressed the increase in the prostate volume and improved the LUTS. Although there is no direct effect on serum testosterone levels, vitamin D supplementation helped improve hypogonadal symptoms.

Notes:

pISSN: 2287-4208 / eISSN: 2287-4690 World J Mens Health Published online M D, 2022 https://doi.org/10.5534/wjmh.220180

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Citation

Bibliographic Citation:

pISSN: 2287-4208 / eISSN: 2287-4690 World J Mens Health Published online M D, 2022 https://doi.org/10.5534/wjmh.220180

Other Study-Related Materials

Label:

비타민 D 연구 실험군 raw data.xlsx

Notes:

application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

Other Study-Related Materials

Label:

비타민D 대조군_raw data.xlsx

Notes:

application/vnd.openxmlformats-officedocument.spreadsheetml.sheet