Stiffness of the Central Corpus Cavernosum on Shear-Wave Elastography Is Inversely Correlated with the Penile Rigidity Score in Patients with Erectile Dysfunction (doi:10.7910/DVN/RFM11L)

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Part 2: Study Description
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Stiffness of the Central Corpus Cavernosum on Shear-Wave Elastography Is Inversely Correlated with the Penile Rigidity Score in Patients with Erectile Dysfunction

doi:10.7910/DVN/RFM11L

Harvard Dataverse

2020-01-07

1

Dae Chul Jung, 2020, "Stiffness of the Central Corpus Cavernosum on Shear-Wave Elastography Is Inversely Correlated with the Penile Rigidity Score in Patients with Erectile Dysfunction", https://doi.org/10.7910/DVN/RFM11L, Harvard Dataverse, V1, UNF:6:xOAzuK5fVS7XTu6seh0RNw== [fileUNF]

Stiffness of the Central Corpus Cavernosum on Shear-Wave Elastography Is Inversely Correlated with the Penile Rigidity Score in Patients with Erectile Dysfunction

doi:10.7910/DVN/RFM11L

Dae Chul Jung (Department of Radiology, Yonsei Severance Hospital, Yonsei University College of Medicine)

Harvard Dataverse

Dae Chul Jung

Park, Hyun Jun

2020-01-07

https://doi.org/10.7910/DVN/RFM11L

Medicine, Health and Life Sciences, Elastography; Erectile dysfunction; Penis; Ultrasonography

Purpose: To perform real-time quantitative measurements of penile rigidity for patients with erectile dysfunction (ED) using shear-wave elastography (SWE). Materials and Methods: A total of 92 patients with clinically diagnosed ED filled out an abridged five-item version of the International Index of Erectile Function (IIEF-5) questionnaire and underwent SWE as well as penile color Doppler ultrasound (CDUS) after intracavernosal injection for penile erection. Elasticity measurements were repeated on two sites of the corpus cavernosum (central and peripheral elasticity of corpus cavernosum [ECC]) and the glans penis during the erection phase. Correlations between penile elasticity and rigidity scores or IIEF-5 were evaluated statistically. Penile elasticity was also compared with the ED types based on CDUS. Results: The mean age of all patients was 53.5±13.4 years, and the mean IIEF-5 score was 9.78±5.01. The rigidity score and central ECC value demonstrated a significant correlation (r=-0.272; 95% confidence interval: -0.464 to -0.056; p=0.015). The IIEF-5 score was not significantly correlated with penile elasticity. Vascular ED patients showed significantly higher central ECC values than nonvascular ED patients (p<0.001). At a cut-off value of 8.05 kPa, the central ECC had a specificity of 41.5%, a sensitivity of 84.6%, and an area under the ROC curve of 0.720 with a standard error of 0.059 (p=0.019) for predicting vascular ED. Conclusions: Quantitatively measuring Young’s modulus of the corpus cavernosum using SWE could be an objective technique for assessing penile erectile rigidity and the vascular subtype in patients with ED.

<a href="http://creativecommons.org/publicdomain/zero/1.0">CC0 1.0</a>

pISSN: 2287-4208 / eISSN: 2287-4690 World J Mens Health Published online M D, 2020 https://doi.org/10.5534/wjmh.190094

https://doi.org/10.5534/wjmh.190094

pISSN: 2287-4208 / eISSN: 2287-4690 World J Mens Health Published online M D, 2020 https://doi.org/10.5534/wjmh.190094

• Number of cases: 92

• No. of variables per record: 35

• Type of File: text/tab-separated-values

UNF:6:xOAzuK5fVS7XTu6seh0RNw==

• deID_serial - deID_serial
• Selection - Selection
• CC_clinic - CC_clinic
• Dx_Dop - Dx_Dop
• IIEF_Total - IIEF_Total
• IIEF_1 - IIEF_1
• IIEF_2 - IIEF_2
• IIEF_3 - IIEF_3
• IIEF_4 - IIEF_4
• IIEF_5 - IIEF_5
• TrT - TrT
• DM - DM
• HTN - HTN
• Ht.Dz - Ht.Dz
• Ca - Ca
• Age - Age
• Mac - Mac
• Rprecad - Rprecad
• Lprecad - Lprecad
• GP_res - GP_res
• Tinj - Tinj
• dose - dose
• Rpostcad - Rpostcad
• Lpostcad - Lpostcad
• Rpsv - Rpsv
• Redv - Redv
• Lpsv - Lpsv
• Ledv - Ledv
• ddv - ddv
• Rigidity - Rigidity
• EC_mean - EC_mean
• ED_mean - ED_mean
• GP - GP
• P_OP - P_OP
• ECCmean - ECCmean

f3655326 Location:

Summary Statistics: Mean 46.5; Max. 92.0; Valid 92.0; StDev 26.70205984563738; Min. 1.0

Variable Format: numeric

Notes: UNF:6:50QxhsYUmyKqgjDrhX6Yqw==

f3655326 Location:

Summary Statistics: StDev 0.0; Mean 1.0; Valid 92.0; Max. 1.0; Min. 1.0;

Variable Format: numeric

Notes: UNF:6:098s3P0JPJuyYZYPQR/52Q==

f3655326 Location:

Summary Statistics: Min. 0.0; Max. 2.0; StDev 0.3115253872088969; Valid 88.0; Mean 0.07954545454545452

Variable Format: numeric

Notes: UNF:6:47j2Y1pATvAbwQ9VQRFvtw==

f3655326 Location:

Summary Statistics: Min. 0.0; Valid 92.0; StDev 1.189016464516193; Max. 3.0; Mean 1.2826086956521738

Variable Format: numeric

Notes: UNF:6:mPSF+2YN82mAJsopV7Qj5w==

f3655326 Location:

Summary Statistics: Max. 22.0; Mean 9.728260869565217; Min. 1.0; Valid 92.0; StDev 5.212207270868642

Variable Format: numeric

Notes: UNF:6:U/Hozjs9ftgx6dr03u0M4A==

f3655326 Location:

Summary Statistics: Max. 5.0; Mean 2.108695652173913; Valid 92.0; Min. 0.0; StDev 0.9772862374304667

Variable Format: numeric

Notes: UNF:6:VNDGn4T9OWxn7z+SJg9vWw==

f3655326 Location:

Summary Statistics: Min. 0.0; Mean 2.0434782608695654; Valid 92.0; StDev 1.1665017060816707; Max. 5.0

Variable Format: numeric

Notes: UNF:6:U7VeU0Rc2mozATIpfHUyhw==

f3655326 Location:

Summary Statistics: Max. 5.0; StDev 1.2776796784508355; Min. 0.0; Valid 92.0; Mean 1.8369565217391304

Variable Format: numeric

Notes: UNF:6:enrbBV0lNRtKkhwTNduBtg==

f3655326 Location:

Summary Statistics: Min. 0.0; Mean 2.0652173913043477; Valid 92.0; Max. 5.0; StDev 1.5321058396436071;

Variable Format: numeric

Notes: UNF:6:ax1R5aVNSmb2x8TXKFzbQg==

f3655326 Location:

Summary Statistics: StDev 1.2234763626396252; Min. 0.0; Max. 5.0; Valid 92.0; Mean 1.673913043478261

Variable Format: numeric

Notes: UNF:6:7aq2+sOQsg2+6MvK1flNiw==

f3655326 Location:

Summary Statistics: Mean 0.0543478260869565; StDev 0.227944972865301; Valid 92.0; Min. 0.0; Max. 1.0

Variable Format: numeric

Notes: UNF:6:LD6QfUWQlTWmRTRW1eacIA==

f3655326 Location:

Summary Statistics: Valid 92.0; Mean 0.2934782608695652; Min. 0.0; StDev 0.4578507717505198; Max. 1.0;

Variable Format: numeric

Notes: UNF:6:5xXSCfeqfocrESXi4CFPnw==

f3655326 Location:

Summary Statistics: Max. 1.0; StDev 0.39024781718172175; Min. 0.0; Mean 0.18478260869565208; Valid 92.0;

Variable Format: numeric

Notes: UNF:6:TAr7jg+o1LmacnFOdoRI2g==

f3655326 Location:

Summary Statistics: StDev 0.10425720702853719; Mean 0.010869565217391283; Max. 1.0; Valid 92.0; Min. 0.0

Variable Format: numeric

Notes: UNF:6:d7CK2D+myTIgNj9CSG2Ahw==

f3655326 Location:

Summary Statistics: Max. 1.0; Mean 0.20652173913043478; StDev 0.4070273765196915; Valid 92.0; Min. 0.0

Variable Format: numeric

Notes: UNF:6:XJ/CdVflQnoCnOnhpE+G5g==

f3655326 Location:

Summary Statistics: Min. 19.0; Valid 92.0; Mean 53.44565217391305; StDev 13.43307720912297; Max. 75.0;

Variable Format: numeric

Notes: UNF:6:Icr9ed1HdhytlZlqHHA5WA==

f3655326 Location:

Summary Statistics: Mean 1.0; Min. 1.0; Valid 59.0; StDev 0.0; Max. 1.0

Variable Format: numeric

Notes: UNF:6:3mQs9ZRjE1Dg+Spk9yJzaw==

f3655326 Location:

Summary Statistics: Valid 45.0; Mean 5.388888888888888; Max. 10.0; Min. 0.5; StDev 2.877042533118643

Variable Format: numeric

Notes: UNF:6:A7NKo3O55XmzLC3qC5crqg==

f3655326 Location:

Summary Statistics: Valid 46.0; Max. 12.0; Min. 0.5; StDev 3.370545906844309; Mean 5.617391304347826

Variable Format: numeric

Notes: UNF:6:lynIxDj9Czy4wkTU7+dUxQ==

f3655326 Location:

Summary Statistics: Min. 7.3; Valid 24.0; Max. 36.3; Mean 16.641666666666666; StDev 6.565053505968697

Variable Format: numeric

Notes: UNF:6:hGPDuMPAZlqvcAy8f5z8MQ==

f3655326 Location:

Variable Format: character

Notes: UNF:6:7uKgwhTOvRZYRcyEgMESSA==

f3655326 Location:

Variable Format: character

Notes: UNF:6:QGIG+y1wBuOpvncb8DQBuQ==

f3655326 Location:

Summary Statistics: StDev 4.989558178962946; Max. 20.0; Min. 0.9; Valid 46.0; Mean 9.517391304347827

Variable Format: numeric

Notes: UNF:6:4nKq41WtlZpILP1qY4gFVw==

f3655326 Location:

Summary Statistics: Mean 9.179166666666665; StDev 4.733760968595839; Min. 0.8; Valid 48.0; Max. 18.0;

Variable Format: numeric

Notes: UNF:6:pQ6+bv+FLPodVRgksegzNw==

f3655326 Location:

Summary Statistics: Max. 93.0; Mean 38.104835164835166; Min. 6.74; Valid 91.0; StDev 17.048912468583335;

Variable Format: numeric

Notes: UNF:6:GHchf2mfhYxE0gOWSyJDIg==

f3655326 Location:

Variable Format: character

Notes: UNF:6:2VU3INbcZM4CHBHLkio37Q==

f3655326 Location:

Summary Statistics: Min. 7.0; StDev 18.84505868587936; Mean 39.058241758241756; Valid 91.0; Max. 110.0

Variable Format: numeric

Notes: UNF:6:AMf7cdExpWoUFdNfUTA4Xg==

f3655326 Location:

Variable Format: character

Notes: UNF:6:aC00Y8T336h1ZqnlWG1JYA==

f3655326 Location:

Summary Statistics: StDev 5.159060615983683; Mean 7.8157575757575755; Min. 2.0; Valid 33.0; Max. 20.0;

Variable Format: numeric

Notes: UNF:6:EnItjRATII3818OHOXy2WQ==

f3655326 Location:

Summary Statistics: Mean 54.347826086956516; Min. 10.0; Max. 100.0; StDev 20.478042264884333; Valid 92.0

Variable Format: numeric

Notes: UNF:6:cf87EMWcH22gwvNjHzVUgw==

f3655326 Location:

Summary Statistics: Valid 64.0; Min. 4.0; Max. 48.9; StDev 10.55290355534204; Mean 16.1013671875;

Variable Format: numeric

Notes: UNF:6:aJbZcs+2eyjqa0j1zkDHuw==

f3655326 Location:

Summary Statistics: Max. 29.0; StDev 4.644261114367579; Mean 8.334754140804348; Valid 92.0; Min. 1.9

Variable Format: numeric

Notes: UNF:6:PT6T3nQp7jqOuqgExhucyw==

f3655326 Location:

Summary Statistics: StDev 9.180585354171201; Min. 3.2; Max. 54.95; Mean 16.84094202927536; Valid 69.0

Variable Format: numeric

Notes: UNF:6:I16b6c7DvLPWEucxgYv7Wg==

f3655326 Location:

Summary Statistics: Max. 1.0; Valid 92.0; Min. 0.0; Mean 0.1521739130434782; StDev 0.36115755925730747

Variable Format: numeric

Notes: UNF:6:+gXdfyc2K7TrW8C6zeLKCA==

f3655326 Location:

Summary Statistics: StDev 6.8337143380276775; Mean 12.337095238283334; Valid 60.0; Min. 2.95; Max. 38.95

Variable Format: numeric

Notes: UNF:6:KODCoXYNyNTmBAyHAoaxhQ==