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Part 1: Document Description
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Citation |
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Title: |
Data for: Mosquitocidal effect and pharmacokinetics of different ivermectin dose regimens in preparation for BOHEMIA cluster randomized controlled trial |
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Identification Number: |
doi:10.7910/DVN/SOBL4B |
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Distributor: |
Harvard Dataverse |
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Date of Distribution: |
2023-04-20 |
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Version: |
2 |
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Bibliographic Citation: |
Maia, Marta F.; Kamau, Yvonne; Tuwei, Mercy; Ominde, Kelly; Ngama, Mwanajuma; Karisa, Jonathan; Babu, Lawrence; Muturi, Martha; Lewa,Frida; Mure, Festus; Mwatasa, Mwaganyuma; Wanjiku, Caroline; Adetifa, Jane; Kern, Charlotte; Duthaler, Urs; Hammann,Felix; Rabinovich,Regina; Chaccour, Carlos, 2023, "Data for: Mosquitocidal effect and pharmacokinetics of different ivermectin dose regimens in preparation for BOHEMIA cluster randomized controlled trial", https://doi.org/10.7910/DVN/SOBL4B, Harvard Dataverse, V2 |
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Citation |
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Title: |
Data for: Mosquitocidal effect and pharmacokinetics of different ivermectin dose regimens in preparation for BOHEMIA cluster randomized controlled trial |
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Identification Number: |
doi:10.7910/DVN/SOBL4B |
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Authoring Entity: |
Maia, Marta F. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Kamau, Yvonne (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Tuwei, Mercy (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Ominde, Kelly (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Ngama, Mwanajuma (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Karisa, Jonathan (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Babu, Lawrence (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Muturi, Martha (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Lewa,Frida (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Mure, Festus (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Mwatasa, Mwaganyuma (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Wanjiku, Caroline (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Adetifa, Jane (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
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Kern, Charlotte (Division of Clinical Pharmacology & Toxicology, Department of Internal Medicine, University Hospital Bern, Switzerland) |
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Duthaler, Urs (Division of Clinical Pharmacology & Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel,Switzerland) |
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Hammann,Felix (Division of Clinical Pharmacology & Toxicology, Department of Internal Medicine, University Hospital Bern, Switzerland) |
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Rabinovich,Regina (ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain) |
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Chaccour, Carlos (ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain) |
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Distributor: |
Harvard Dataverse |
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Access Authority: |
Mwango, Lillian |
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Depositor: |
Maia, Marta F. |
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Date of Deposit: |
2023-04-12 |
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Holdings Information: |
https://doi.org/10.7910/DVN/SOBL4B |
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Study Scope |
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Keywords: |
Medicine, Health and Life Sciences, Anopheles gambiae, malaria, ivermectin, mass drug administration |
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Abstract: |
<p>The aim of the trial was to compare the pharmacokinetics and mosquito-killing effect of 300 mcg/kg of IVM given on three consecutive days to 400 mcg/kg of IVM given once. The trial also evaluated how the two treatments differed from albendazole in terms of mosquito survival</p> <p>Mosquitocidal effect and pharmacokinetics of different ivermectin dose regimens given to both male and female healthy participants who were willing to comply with study requirements. The study participants were residents of Ngerenya, Kilifi, Kenya</p> <p>The datasets describe the process of screening the participants and randomization into the study arms for eligible individuals. Participants screened 30 days to study allocation were screened again to check on their eligibility. Participants were treated and followed up according to the group to which the participant was assigned. Participants who were dropped off from the study were registered in the withdrawal form. </p> <p>The trial is registered on clinicaltrials.gov: NCT04966702</p> |
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Kind of Data: |
Clinical Trial |
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Kind of Data: |
Restricted |
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Notes: |
<p><strong>Data Access: </strong>Restricted</p> <p>Access to these data requires submission of a formal request for consideration by our Data Governance Committee. </p> <strong>How to request</strong> <ol> <li>Download and complete the <a href="https://kemri-wellcome.org/zp-content/uploads/2021/02/KWTRP_Dataverse_Data_Request_Form_2019.docx"><strong>data request form</strong></a></li> <li> Email completed data request form to the Data Governance Committee at <a href="mailto:dgc@kemri-wellcome.org?cc=lmwango@kemri-wellcome.org?Subject=Data%20Access%20Request"><strong>dgc@kemri-wellcome.org</strong></a> </li> </ol> |
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Methodology and Processing |
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Sources Statement |
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Data Access |
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Notes: |
For access to data and more detailed information beyond the metadata and documentation provided, please send a signed data request form to [<a href="mailto:dgc@kemri-wellcome.org">dgc@kemri-wellcome.org</a> ]. <strong> <a href="https://kemri-wellcome.org/zp-content/uploads/2021/02/KWTRP_Dataverse_Data_Request_Form_2019.docx">Click to download Data Request Form</a></strong> |
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Other Study Description Materials |
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Related Publications |
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Citation |
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Bibliographic Citation: |
Manuscripts in preparation |
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Label: |
CRFs.zip |
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Notes: |
application/zip |
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Label: |
datasets.zip |
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Notes: |
application/zip |
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Label: |
MMAIA_PK400_Readme.TXT.txt |
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Notes: |
text/plain |