Pregnancy-associated breast cancer (PABC): a matched case-control study of young women (doi:10.7910/DVN/SR06ED)

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Document Description

Citation

Title:

Pregnancy-associated breast cancer (PABC): a matched case-control study of young women

Identification Number:

doi:10.7910/DVN/SR06ED

Distributor:

Harvard Dataverse

Date of Distribution:

2023-01-04

Version:

1

Bibliographic Citation:

Yang, Zhifen, 2023, "Pregnancy-associated breast cancer (PABC): a matched case-control study of young women", https://doi.org/10.7910/DVN/SR06ED, Harvard Dataverse, V1

Study Description

Citation

Title:

Pregnancy-associated breast cancer (PABC): a matched case-control study of young women

Identification Number:

doi:10.7910/DVN/SR06ED

Authoring Entity:

Yang, Zhifen

Distributor:

Harvard Dataverse

Access Authority:

Yang, Zhifen

Depositor:

Yang, Zhifen

Date of Deposit:

2023-01-04

Holdings Information:

https://doi.org/10.7910/DVN/SR06ED

Study Scope

Keywords:

Medicine, Health and Life Sciences

Abstract:

To compare the clinical characteristics and prognosis of pregnancy-associated breast cancer (PABC) patients and non-PABC subjects in Hebei Breast Disease Treatment Center. A total of 40 PABC patients, including 10 pregnant women and 30 postpartum women, and 80 non-PABC subjects were recruited. The mean age of pregnancy in PABC patients was significantly older than that of non-PABC subjects (26.8 years vs. 23.5 years, P<0.05). Categorized by the receptor status, the ratio of hormone receptor (HR) positive breast cancer was lower in PABC patients than that of non-PABC subjects (57.5% vs. 70.0%, P=0.221), while the ratios of HER2- (42.5% vs. 37.5%, P=0.692) and triple-negative PABC patients (20% vs. 12.5%, P=0.578) were higher than those of non-PABC patients, although no significant differences were detected. There were no significant differences in the DFS (54.2 months vs. 63.5 months, P=0.271) and OS (54.2 months vs. 65.4 months, P=0.116) between PABC patients and non-PABC subjects. Compared with non-PABC subjects, the average age of pregnancy of PABC patients was later, while share similar pathological characteristics, as well as DFS and OS.

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Data .xlsx

Notes:

application/vnd.openxmlformats-officedocument.spreadsheetml.sheet