Replication Data for: Age structure and parity status determination of Afrotropical malaria vectors using MALDI-TOF MS (doi:10.7910/DVN/VJQXH3)

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Part 1: Document Description
Part 2: Study Description
Part 3: Data Files Description
Part 4: Variable Description
Part 5: Other Study-Related Materials
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Document Description

Citation

Title:

Replication Data for: Age structure and parity status determination of Afrotropical malaria vectors using MALDI-TOF MS

Identification Number:

doi:10.7910/DVN/VJQXH3

Distributor:

Harvard Dataverse

Date of Distribution:

2025-02-20

Version:

1

Bibliographic Citation:

Tuwei, Mercy; Karisa, Jonathan; Kiuru, Caroline; Ondieki, Zedekiah; Odongo, Tobias; Muturi,Martha; Mure, Festus; Otieno, Bruno; Akoko,Miguel; Gona, Rehema; Ominde, Kelly; Constantino,Luis; Cole, Gildo; Anastácio, Trisa; Candrinho, Baltazar; Armazia, Romário; Alves, Claudia; Ramaitha, Edith; Rono, Martin; Mwangangi, Joseph; Mbogo, Charles; Wanjiku, Caroline; Chaccour, Carlos; Maia, Marta, 2025, "Replication Data for: Age structure and parity status determination of Afrotropical malaria vectors using MALDI-TOF MS", https://doi.org/10.7910/DVN/VJQXH3, Harvard Dataverse, V1, UNF:6:IXeYXAiq8I+SUHmB2PlgOw== [fileUNF]

Study Description

Citation

Title:

Replication Data for: Age structure and parity status determination of Afrotropical malaria vectors using MALDI-TOF MS

Identification Number:

doi:10.7910/DVN/VJQXH3

Authoring Entity:

Tuwei, Mercy (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Karisa, Jonathan (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Kiuru, Caroline (Centro de Investigação em Saúde de Manhiça; Bairro Cambeve. Rua 12, Distrito da Manhiça, CP 1929, Maputo, Moçambique/CIBER de Enfermedades Infecciosas, 28029, Madrid, Spain)

Ondieki, Zedekiah (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Odongo, Tobias (KEMRI-CGMR Coast Kilifi)

Muturi,Martha (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Mure, Festus (KEMRI-CGMR Coast Kilifi)

Otieno, Bruno (KEMRI-CGMR Coast Kilifi)

Akoko,Miguel (KEMRI-CGMR Coast Kilifi)

Gona, Rehema (KEMRI-CGMR Coast Kilifi)

Ominde, Kelly (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Constantino,Luis (Centro de Investigação em Saúde de Manhiça; Bairro Cambeve. Rua 12, Distrito da Manhiça, CP 1929, Maputo, Moçambique)

Cole, Gildo (Centro de Investigação em Saúde de Manhiça; Bairro Cambeve. Rua 12, Distrito da Manhiça, CP 1929, Maputo, Moçambique)

Anastácio, Trisa (Centro de Investigação em Saúde de Manhiça; Bairro Cambeve. Rua 12, Distrito da Manhiça, CP 1929, Maputo, Moçambique)

Candrinho, Baltazar (National malaria Control Program, Maputo, Mozambique)

Armazia, Romário (Centro de Investigação em Saúde de Manhiça; Bairro Cambeve. Rua 12, Distrito da Manhiça, CP 1929, Maputo, Moçambique)

Alves, Claudia (Centro de Investigação em Saúde de Manhiça; Bairro Cambeve. Rua 12, Distrito da Manhiça, CP 1929, Maputo, Moçambique)

Ramaitha, Edith (National Malaria Control Program, Ministry of Health, Kenya)

Rono, Martin (KEMRI-CGMR Coast Kilifi)

Mwangangi, Joseph (KEMRI-CGMR Coast Kilifi)

Mbogo, Charles (KEMRI-CGMR Coast Kilifi)

Wanjiku, Caroline (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)

Chaccour, Carlos (ISGlobal, Carrer Roselló 132, 08036, Barcelona, Spain/CIBER de Enfermedades Infecciosas, 28029, Madrid, Spain/Navarra Center for International Development, Universidad de Navarra, 31009, Pamplona, Spain)

Maia, Marta (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya//University of Oxford, Centre for Global Health and Tropical Medicine, Oxford, UK)

Distributor:

Harvard Dataverse

Access Authority:

Tuwei, Mercy

Access Authority:

Maia, Marta

Access Authority:

The Data Governance Committee

Depositor:

Tuwei, Mercy

Date of Deposit:

2025-02-19

Holdings Information:

https://doi.org/10.7910/DVN/VJQXH3

Study Scope

Keywords:

Medicine, Health and Life Sciences, MALDI-TOF MS

Abstract:

<p>This is a replication dataset for the manuscript titled: "<i><strong>Age structure and parity status determination of Afrotropical malaria vectors using MALDI-TOF MS.</strong></i>"</p> <p>The age structure of a mosquito population helps estimate the proportion of vectors capable of transmitting malaria. Many malaria transmission models rely on mosquito longevity as key parameter. However, these are rarely measured in the field due to lack of a reliable and scalable age-grading method. An accurate method could improve predictions of malaria risk and the impact assessment of interventions. This study aimed to investigate the use of MALDI-TOF MS for malaria vector age-grading using insectary-reared and wild-caught mosquitoes. Anopheles gambiae s.s. mosquitoes were reared in the insectary to different known physiological and chronological ages to evaluate if MALDI-TOF MS could be used to distinguish between different age groups. Wild mosquitoes were collected in Mozambique and dissected to determine their parity status. Reference spectra were obtained from mosquito’s cephalothorax and used to create predictive databases which were validated using independent samples. </p>

Kind of Data:

Open Access

Methodology and Processing

Sources Statement

Data Access

Other Study Description Materials

File Description--f10896869

File: CDCD_KENYA_PARITY_MALDI-TOF MS_ 18022025_F.tab

  • Number of cases: 448

  • No. of variables per record: 6

  • Type of File: text/tab-separated-values

Notes:

UNF:6:kSBVEvXdHbQmRQsVucNm+A==

List of all mosquito samples used to create database and testing including information on mosquito age

File Description--f10896868

File: Chrinological age_18022025_F.tab

  • Number of cases: 442

  • No. of variables per record: 8

  • Type of File: text/tab-separated-values

Notes:

UNF:6:dD0Lu4FaviGtp+sxwou/aw==

List of all mosquito samples used to create database and testing including information on mosquito age

File Description--f10896870

File: MZ_Parity_MALDI-TOF MS_18022025_F.tab

  • Number of cases: 1946

  • No. of variables per record: 6

  • Type of File: text/tab-separated-values

Notes:

UNF:6:UxzPl2/HUz2/UmSCiFKUJQ==

List of all mosquito samples used to create database and testing including information on mosquito age

File Description--f10896871

File: Physiological age_ 18022025_ F.tab

  • Number of cases: 357

  • No. of variables per record: 8

  • Type of File: text/tab-separated-values

Notes:

UNF:6:GhyE7zZt+WEbGhxm7aUhpA==

List of all mosquito samples used to create database and testing including information on mosquito age

Variable Description

List of Variables:

Variables

Sample ID

f10896869 Location:

Variable Format: character

Notes: UNF:6:i6TQCT/j/HTAb9hFI0JcrA==

parity status_Dissection

f10896869 Location:

Variable Format: character

Notes: UNF:6:YcZnlwaBmhVuy7nFE3EDAw==

MALDI-TOF MS SPP

f10896869 Location:

Variable Format: character

Notes: UNF:6:fBW6vc7N/0UURwgL5xew1w==

LSV SPP

f10896869 Location:

Variable Format: character

Notes: UNF:6:i7CeFMjY1P9zZIDIKJKFIA==

MALDI-TF MS Parity

f10896869 Location:

Variable Format: character

Notes: UNF:6:UpNk85oBcCXhEuM9XoG9zA==

LSV Parity

f10896869 Location:

Variable Format: character

Notes: UNF:6:EaZigUl+LNQaoSRsNRxiqw==

ID NO

f10896868 Location:

Variable Format: character

Notes: UNF:6:rsIYF/CQloDSj2jUOcRFZg==

Age

f10896868 Location:

Variable Format: character

Notes: UNF:6:S/SGwDAFzie+ABkyp0BLfg==

Status

f10896868 Location:

Variable Format: character

Notes: UNF:6:LW3YmZmao1BWHAZU7+BU/Q==

Mating Status

f10896868 Location:

Variable Format: character

Notes: UNF:6:eGG3TTYDRp1bGhjQd/U/jA==

Species

f10896868 Location:

Variable Format: character

Notes: UNF:6:JHdaPFt5eeBCVH7ghjIj0Q==

MALDI_Age

f10896868 Location:

Variable Format: character

Notes: UNF:6:NrpIc/PDSr7Uv+m/SjLJzQ==

Log_score_value

f10896868 Location:

Summary Statistics: Min. 1.8; Max. 218.0; Mean 2.914913580246913; StDev 10.71630213693317; Valid 405.0;

Variable Format: numeric

Notes: UNF:6:4od1uXQd8GdDESRtpC/EMA==

Age Status

f10896868 Location:

Variable Format: character

Notes: UNF:6:eRlvzlgmLvFoeI8bw+HlrA==

sample ID

f10896870 Location:

Variable Format: character

Notes: UNF:6:4Sz22z/j+GaiABl04uA8+A==

parity status_Dissection

f10896870 Location:

Variable Format: character

Notes: UNF:6:w3SThMcO9v8xizBaiqTbfw==

MALDI-TOF MS SPP

f10896870 Location:

Variable Format: character

Notes: UNF:6:CUN+PpxjbXthiqY2tok7+Q==

LSV SPP

f10896870 Location:

Variable Format: character

Notes: UNF:6:rlVUd9+YKFS4rKTcn8zOEA==

MALDI-TOF MS Parity Status

f10896870 Location:

Variable Format: character

Notes: UNF:6:W0eMT+IWiwXsWaPBVA8eqw==

LSV Parity

f10896870 Location:

Variable Format: character

Notes: UNF:6:idO3r+6HrOA0NuGUFG4Qfw==

ID NO

f10896871 Location:

Variable Format: character

Notes: UNF:6:3dGr4UE/1MlL9qaNmUFkJA==

Age

f10896871 Location:

Variable Format: character

Notes: UNF:6:HMg3qSFUO1jj6GfMfh7qpw==

Status

f10896871 Location:

Variable Format: character

Notes: UNF:6:M+oo7JlKkhf3CsDYNNlk/A==

Mating Status

f10896871 Location:

Variable Format: character

Notes: UNF:6:sWuHQ9sm09WcOLl0a9XSXA==

Species

f10896871 Location:

Variable Format: character

Notes: UNF:6:YKW8H51AzJRroHICGhlnUw==

MALDI_Age

f10896871 Location:

Variable Format: character

Notes: UNF:6:Mblyp8R58NPlzJIO/GcQkw==

Log_score_value

f10896871 Location:

Summary Statistics: Max. 2.76; Min. 1.7; Valid 310.0; StDev 0.17636903097530993; Mean 2.444622580645161;

Variable Format: numeric

Notes: UNF:6:DKlYACEg9xZFekqChmMZ/w==

Age Status

f10896871 Location:

Variable Format: character

Notes: UNF:6:pePCBWHYCakrrv995xGULw==

Other Study-Related Materials

Label:

Age structure_and_parity status determination_MALDI-TOF MS_Readme.txt

Notes:

text/plain

Other Study-Related Materials

Label:

Age structure_and_parity status determination_MALDI-TOF MS_R_Codes_18022025.R

Notes:

type/x-r-syntax

Other Study-Related Materials

Label:

AUTHOR_DATASET_CodebookTemplate_Blank2.xlsx

Text:

Describes variable names descriptions and value labels

Notes:

application/vnd.openxmlformats-officedocument.spreadsheetml.sheet