Replication Data for: 10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity (doi:10.7910/DVN/X4L47D)

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Part 1: Document Description
Part 2: Study Description
Part 3: Data Files Description
Part 4: Variable Description
Part 5: Other Study-Related Materials
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Replication Data for: 10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity

doi:10.7910/DVN/X4L47D

Harvard Dataverse

2021-01-06

2

Langhorne, Jean; Addy, John, 2021, "Replication Data for: 10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity", https://doi.org/10.7910/DVN/X4L47D, Harvard Dataverse, V2, UNF:6:B3wkC5jquisSY6YqmnOeVg== [fileUNF]

Replication Data for: 10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity

doi:10.7910/DVN/X4L47D

Langhorne, Jean (Francis Crick Institute)

Addy, John (Francis Crick Institute)

Harvard Dataverse

Langhorne, Jean

Addy, John

Mwango, Lillian

2021-01-05

Medicine, Health and Life Sciences

<p> This is a replication dataset for the manuscript for the manuscript titled: "<a href="">10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity</a>" submitted to the Wellcome Open Research Journal. </p> <p> This dataset contains information on the individual clinical malaria episodes of 56 children from the age of 5 to 15. Further information includes asymptomatic parasite densities and antibody titres. </p> <p><b>Related Research Project:</b> A systems biology approach to understand immunity and pathogenesis of malaria in children exposed to endemic Plasmodium falciparum transmission (SIMS). </p>

<p>Publications based on this data collection should acknowledge this source by means of bibliographic citation.</p>

<p> This data is licensed under the <a href="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</a> <a href="https://creativecommons.org/licenses/by/4.0/legalcode"><img src="https://i.creativecommons.org/l/by/3.0/88x31.png"> </a> </p> <p> For more information on these data, please contact the author(s) OR the data governance office via this email address: dgc@kemri-wellcome.org. </p>

• Number of cases: 621

• No. of variables per record: 37

• Type of File: text/tab-separated-values

UNF:6:B3wkC5jquisSY6YqmnOeVg==

• Participant.ID - Participant.ID
• Year - Year
• Episodes - Episodes
• Cumulative.Episodes - Cumulative.Episodes
• Pcr.Pf.Mcl - Pcr.Pf.Mcl
• Pcr.Ps - Pcr.Ps
• Ct - Ct
• Age - Age
• AMA1.3D7.OD.1 - AMA1.3D7.OD.1
• AMA1.3D7.OD.2 - AMA1.3D7.OD.2
• AMA1.3D7.OD - AMA1.3D7.OD
• AMA1.3D7 - AMA1.3D7
• AMA1.FVO.OD.1 - AMA1.FVO.OD.1
• AMA1.FVO.OD.2 - AMA1.FVO.OD.2
• AMA1.FVO.OD - AMA1.FVO.OD
• AMA1.FVO - AMA1.FVO
• AMA1.L32.OD.1 - AMA1.L32.OD.1
• AMA1.L32.OD.2 - AMA1.L32.OD.2
• AMA1.L32.OD - AMA1.L32.OD
• AMA1.L32 - AMA1.L32
• MSP1.3D7.OD.1 - MSP1.3D7.OD.1
• MSP1.3D7.OD.2 - MSP1.3D7.OD.2
• MSP1.3D7.OD - MSP1.3D7.OD
• MSP1.3D7 - MSP1.3D7
• MSP1.FUP.OD.1 - MSP1.FUP.OD.1
• MSP1.FUP.OD.2 - MSP1.FUP.OD.2
• MSP1.FUP.OD - MSP1.FUP.OD
• MSP1.FUP - MSP1.FUP
• MSP1.FVO.OD.1 - MSP1.FVO.OD.1
• MSP1.FVO.OD.2 - MSP1.FVO.OD.2
• MSP1.FVO.OD - MSP1.FVO.OD
• MSP1.FVO - MSP1.FVO
• MSP3.FVO.OD.1 - MSP3.FVO.OD.1
• MSP3.FVO.OD.2 - MSP3.FVO.OD.2
• MSP3.FVO.OD - MSP3.FVO.OD
• MSP3.FVO - MSP3.FVO
• Plateau - Plateau

f4422516 Location:

Variable Format: character

Notes: UNF:6:qVbKhcztAMX0/a4ipHVXOg==

f4422516 Location:

Summary Statistics: StDev 3.282200142383322; Max. 2018.0; Mean 2011.9323671497584; Min. 2006.0; Valid 621.0;

Variable Format: numeric

Notes: UNF:6:jhJAXdx3+HzHMXqyTRb0bA==

f4422516 Location:

Summary Statistics: Min. 0.0; Mean 0.6899350649350654; StDev 1.0605855089491116; Max. 8.0; Valid 616.0

Variable Format: numeric

Notes: UNF:6:VNaZ7Xkk1p+7EaIb7LHPlQ==

f4422516 Location:

Summary Statistics: Max. 32.0; Min. 0.0; StDev 4.908839550575169; Valid 616.0; Mean 4.743506493506496

Variable Format: numeric

Notes: UNF:6:rJNRh1Qr/No7R3Ed/76ySA==

f4422516 Location:

Summary Statistics: Valid 488.0; StDev 22173.332626876996; Max. 406590.0; Min. 0.0; Mean 3599.118205306149

Variable Format: numeric

Notes: UNF:6:xuSgfH3SV2GQyaX3ZXBEgQ==

f4422516 Location:

Variable Format: character

Notes: UNF:6:alM3SOqfkmoLdG5Y43w8BA==

f4422516 Location:

Summary Statistics: Valid 0.0; Mean NaN; Min. NaN; StDev NaN; Max. NaN;

Variable Format: numeric

Notes: UNF:6:pAqLhyQSIAFo8oQHGGOv9A==

f4422516 Location:

Summary Statistics: StDev 3.1617584581786864; Min. 5.0; Mean 10.006472491909385; Valid 618.0; Max. 15.0

Variable Format: numeric

Notes: UNF:6:AqLr9MS3y2a7notxvjwC6Q==

f4422516 Location:

Summary Statistics: Max. 3.9; Mean 1.272075471698113; Min. 0.122; StDev 1.1123886089273873; Valid 53.0;

Variable Format: numeric

Notes: UNF:6:gqFSweQ+2usYz+mytxTAqg==

f4422516 Location:

Summary Statistics: Max. 3.52; Min. 0.121; StDev 1.0918801031485414; Valid 53.0; Mean 1.2572641509433962

Variable Format: numeric

Notes: UNF:6:b0bz8FPprRDXTYh/OFg17A==

f4422516 Location:

Summary Statistics: StDev 1.1038413636788393; Max. 3.76; Mean 1.2656132075471698; Min. 0.1215; Valid 53.0

Variable Format: numeric

Notes: UNF:6:MJwacFxvDBWsSgbFddkAwA==

f4422516 Location:

Summary Statistics: Mean 713.1193733779963; Max. 7573.83442405707; StDev 1449.5020006656746; Valid 53.0; Min. 20.2414240289748

Variable Format: numeric

Notes: UNF:6:pSRkR1o7GXn0UvQ7c9IjBw==

f4422516 Location:

Summary Statistics: StDev 1.1710403255631454; Valid 54.0; Max. 3.9; Mean 1.4659074074074074; Min. 0.15

Variable Format: numeric

Notes: UNF:6:D396u+jTssIjxSvHISLg7A==

f4422516 Location:

Summary Statistics: Max. 3.833; Valid 54.0; Min. 0.15; Mean 1.4623333333333333; StDev 1.1711257445014016

Variable Format: numeric

Notes: UNF:6:KfyEoGSyLsiPS6ChIDWAfw==

f4422516 Location:

Summary Statistics: Max. 3.8665; Min. 0.15; StDev 1.1707661011233126; Mean 1.4641203703703705; Valid 54.0;

Variable Format: numeric

Notes: UNF:6:CimqbV9XBwRgvppYq0Frxg==

f4422516 Location:

Summary Statistics: Min. 31.9332308368053; StDev 1890.0417431689123; Mean 925.5939728693103; Valid 54.0; Max. 10588.2634521225

Variable Format: numeric

Notes: UNF:6:d5IkjLujCtHfFkFZRIPTUQ==

f4422516 Location:

Summary Statistics: Max. 3.9; Mean 1.2725849056603773; Valid 53.0; Min. 0.123; StDev 1.1326932579877294;

Variable Format: numeric

Notes: UNF:6:95xKcXrAPTNROfBj9GdgeA==

f4422516 Location:

Summary Statistics: StDev 1.14067219697769; Valid 53.0; Min. 0.126; Mean 1.2896981132075471; Max. 3.9

Variable Format: numeric

Notes: UNF:6:uJoDb4HNjM2mWo2O8APtVg==

f4422516 Location:

Summary Statistics: Mean 1.2811415094339622; Min. 0.1245; StDev 1.135328630741907; Max. 3.9; Valid 53.0;

Variable Format: numeric

Notes: UNF:6:tYDfMZ2s/LZTtosVn1xIQg==

f4422516 Location:

Summary Statistics: Mean 732.8783741493663; StDev 1551.3526966747972; Valid 53.0; Min. 21.8381265985596; Max. 8224.92649522123;

Variable Format: numeric

Notes: UNF:6:k66q2D3NILcvcFwsOa967g==

f4422516 Location:

Summary Statistics: Valid 54.0; Mean 0.8723518518518518; Min. 0.072; Max. 3.113; StDev 0.691996841453349;

Variable Format: numeric

Notes: UNF:6:uSkB0pxkKGRYJPnFNMxE0A==

f4422516 Location:

Summary Statistics: Max. 3.094; StDev 0.7149708073871219; Valid 54.0; Min. 0.071; Mean 0.8829074074074075;

Variable Format: numeric

Notes: UNF:6:O0Vbi7o3pINTnfIP1GocNQ==

f4422516 Location:

Summary Statistics: StDev 0.7126741147120281; Min. 0.0715; Max. 3.1035; Valid 54.0; Mean 0.8847592592592592

Variable Format: numeric

Notes: UNF:6:HmANmK3/lPt1SeucKgWhag==

f4422516 Location:

Summary Statistics: Mean 663.539792250546; StDev 769.4989169221764; Valid 54.0; Max. 4190.40141283899; Min. 51.983966108164;

Variable Format: numeric

Notes: UNF:6:0Pt1csCQ4jWQfxK2pwqszg==

f4422516 Location:

Summary Statistics: StDev 0.776730581942817; Max. 3.098; Mean 1.0274074074074073; Min. 0.085; Valid 54.0

Variable Format: numeric

Notes: UNF:6:deIXo90gy1BQz2ALRBv7MA==

f4422516 Location:

Summary Statistics: Max. 3.11; StDev 0.7587028258728324; Mean 1.013388888888889; Valid 54.0; Min. 0.082

Variable Format: numeric

Notes: UNF:6:DclkeRGZ6EabVNReWOEkVA==

f4422516 Location:

Summary Statistics: Max. 3.104; Valid 54.0; StDev 0.7662661145440223; Min. 0.0835; Mean 1.020398148148148

Variable Format: numeric

Notes: UNF:6:O83ntdFXA4v2qWb4X9gV+A==

f4422516 Location:

Summary Statistics: Mean 639.8272935772343; Valid 54.0; StDev 768.5008139820347; Min. 45.0429397591003; Max. 4662.61804625583;

Variable Format: numeric

Notes: UNF:6:WmLYa2SZzvfxAHg7LWk25Q==

f4422516 Location:

Summary Statistics: StDev 0.19419585410936457; Mean 0.28632075471698115; Valid 53.0; Min. 0.081; Max. 1.301;

Variable Format: numeric

Notes: UNF:6:zsRoib9efs9HUr79Kjy9QA==

f4422516 Location:

Summary Statistics: Max. 1.286; Min. 0.09; StDev 0.21648428481830878; Mean 0.2996981132075472; Valid 53.0;

Variable Format: numeric

Notes: UNF:6:swqNh8rBPByy5brin4SMFg==

f4422516 Location:

Summary Statistics: Mean 0.30156603773584906; Valid 53.0; Min. 0.0855; Max. 1.2935; StDev 0.2178651231870449

Variable Format: numeric

Notes: UNF:6:ky7XPsueHEco1TNU862GqA==

f4422516 Location:

Summary Statistics: Max. 1924.91537471753; Mean 336.3619455721024; Min. 97.6128031698797; Valid 53.0; StDev 320.57227582374014

Variable Format: numeric

Notes: UNF:6:0ojlnM9rJrh5c+OD3c4yvg==

f4422516 Location:

Summary Statistics: Valid 54.0; StDev 0.7151177284046917; Mean 0.7457407407407407; Max. 3.078; Min. 0.161

Variable Format: numeric

Notes: UNF:6:2Z0lEaOsHjtgBeqf0hU8TA==

f4422516 Location:

Summary Statistics: StDev 0.7105784714941366; Valid 54.0; Min. 0.177; Mean 0.7381666666666666; Max. 3.146;

Variable Format: numeric

Notes: UNF:6:jGcj4XnfPl7FguGlQ0I1Ig==

f4422516 Location:

Summary Statistics: Mean 0.7419537037037037; StDev 0.7119705266617996; Min. 0.169; Max. 3.112; Valid 54.0;

Variable Format: numeric

Notes: UNF:6:SD9Ow+fjuli8ej62YMZirA==

f4422516 Location:

Summary Statistics: Min. 126.819869603657; Mean 965.7398920824327; Max. 7349.72159602953; StDev 1491.4985507883162; Valid 54.0;

Variable Format: numeric

Notes: UNF:6:2v8qWnNoMDbKQXo6DX8KLA==

f4422516 Location:

Summary Statistics: Valid 621.0; Mean 0.389694041867955; Max. 1.0; Min. 0.0; StDev 0.48807396628095273

Variable Format: numeric

Notes: UNF:6:M+q1LX5mABhoO+0MbnEQmg==

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