|
View: |
Part 1: Document Description
|
|
Citation |
|
|---|---|
|
Title: |
Replication Data for: Induction of an early IFN-γ cellular response and high plasma levels of SDF-1α are inversely associated with COVID-19 severity and residence in rural areas in Kenyan patients |
|
Identification Number: |
doi:10.7910/DVN/XMTCTW |
|
Distributor: |
Harvard Dataverse |
|
Date of Distribution: |
2024-12-13 |
|
Version: |
1 |
|
Bibliographic Citation: |
Wanjiku, Perpetual; Orindi, Benedict; Kimotho, John; Sayed, Shahin; Shah, Reena; Saleh Mansoor; Mwacharo, Jedidah; Maronga, Christopher; Oluoch, Vivian; Karanu, Ann; Shah, Jasmit; Nneka, Zaitun; Ochola-Oyier, Lynette Isabella; Abdi, Abdirahman I.; Dunachie, Susanna; Bejon, Philip; Nduati, Eunice; Ndungu, Francis M., 2024, "Replication Data for: Induction of an early IFN-γ cellular response and high plasma levels of SDF-1α are inversely associated with COVID-19 severity and residence in rural areas in Kenyan patients", https://doi.org/10.7910/DVN/XMTCTW, Harvard Dataverse, V1, UNF:6:JkMDcIXMDJ5GzzCjZ4ra3A== [fileUNF] |
|
Citation |
|
|
Title: |
Replication Data for: Induction of an early IFN-γ cellular response and high plasma levels of SDF-1α are inversely associated with COVID-19 severity and residence in rural areas in Kenyan patients |
|
Identification Number: |
doi:10.7910/DVN/XMTCTW |
|
Authoring Entity: |
Wanjiku, Perpetual (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
Orindi, Benedict (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Kimotho, John (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Sayed, Shahin (Aga Khan University Hospital) |
|
|
Shah, Reena (Aga Khan University Hospital) |
|
|
Saleh Mansoor (Aga Khan University Hospital) |
|
|
Mwacharo, Jedidah (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Maronga, Christopher (Nuffield Department of Population Health, Cancer Epidemiology Unit) |
|
|
Oluoch, Vivian (Aga Khan University Hospital) |
|
|
Karanu, Ann (Aga Khan University Hospital) |
|
|
Shah, Jasmit (Brain and Mind Institute and Department of Medicine, Aga Khan University) |
|
|
Nneka, Zaitun (Aga Khan University Hospital) |
|
|
Ochola-Oyier, Lynette Isabella (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Abdi, Abdirahman I. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Dunachie, Susanna (Nuffield Department of Medicine, Centre for Global Health Research, University of Oxford) |
|
|
Bejon, Philip (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Nduati, Eunice (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Ndungu, Francis M. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Distributor: |
Harvard Dataverse |
|
Access Authority: |
Wanjiku, Perpetual |
|
Access Authority: |
Ndungu, Francis M. |
|
Access Authority: |
The Data Governance Committee |
|
Depositor: |
Wanjiku, Perpetual |
|
Date of Deposit: |
2024-12-11 |
|
Holdings Information: |
https://doi.org/10.7910/DVN/XMTCTW |
|
Study Scope |
|
|
Keywords: |
Medicine, Health and Life Sciences, COVID-19, SARS-CoV-2, IFN-γ-secreting cells, cytokines, chemokines, kinetics, Sub-Saharan Africa |
|
Abstract: |
<p>This is a replication dataset for the manuscript titled: "<i><strong>Induction of an early IFN-γ cellular response and high plasma levels of SDF-1α are inversely associated with COVID-19 severity and residence in rural areas in Kenyan patients</strong></i>" submitted to the PLOS One journal.</p> <p>The first dataset describes the baseline characteristics of the Kenyan COVID-19 patients, who were included in this analysis, they were recruited from June 2020 to February 2022. Plasma samples were then collected longitudinally over four successive time points within one month of COVID-19 diagnosis. Dataset contains clinical data on underlying conditions and hospital admission of the patients collected during patient care/treatment. Datasets is shared as .CSV Excel files. </p> <p>The second dataset contains concentrations of cytokines and chemokines assayed on plasma samples using Luminex assay. Datasets is shared as .CSV Excel files. </p> <p>The third dataset comprises a subset of 59 patients derived from the second dataset who had at least PBMC samples from 3 timepoints. It contains IFNy secreting cell responses assayed by Elispot for 172 samples. Datasets is shared as .CSV Excel files. </p> |
|
Kind of Data: |
Restricted Access |
|
Methodology and Processing |
|
|
Sources Statement |
|
|
Data Access |
|
|
Other Study Description Materials |
|
|
File Description--f10779432 |
|
|
File: baseline_xtcis_data_anon.tab |
|
|
|
|
Notes: |
UNF:6:hCrYukyBkznb7F/2G7z0Fw== |
|
File Description--f10779430 |
|
|
File: elispot_data_anon.tab |
|
|
|
|
Notes: |
UNF:6:AGxC568zK4YC0AM8fKJEqw== |
|
File Description--f10779431 |
|
|
File: Luminex_data.tab |
|
|
|
|
Notes: |
UNF:6:h1PkUwtuhJX1SUMLzi6hhg== |
|
Label: |
baseline xtics_dataanalysis.R |
|
Text: |
contains statistical codes of analysis for creating Table 1. Participant demographic and clinical characteristics. |
|
Notes: |
type/x-r-syntax |
|
Label: |
ELISpot_dataanalysis.prism |
|
Text: |
LISpot_dataanalysis- Contains statistical analysis for Elispot_data |
|
Notes: |
application/octet-stream |
|
Label: |
luminex_dataanalysis.R |
|
Text: |
Contains statistical codes for analysing Luminex data. |
|
Notes: |
type/x-r-syntax |
|
Label: |
PWanjiku_ImmunoCov_data_dictionary_2024.pdf |
|
Notes: |
application/pdf |
|
Label: |
readme_ImmunoCoV.txt |
|
Notes: |
text/plain |