Data for: A multicenter, prospective observational study of intraleukocytic and intraerythrocytic pigment as prognostic features in African children with falciparum malaria

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Olola, Christopher; Agbenyega, Tsiri; Kremsner, Peter Gottfried; Newton, Charles R.; Bojang, Kalifa; Taylor, Terrie, 2020, "Data for: A multicenter, prospective observational study of intraleukocytic and intraerythrocytic pigment as prognostic features in African children with falciparum malaria", https://doi.org/10.7910/DVN/0CTWUJ, Harvard Dataverse, V2

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Description	This data collection was generated by a study of the prognostic significance of circulating pigment conducted by consortium of research units at five sites (Kenya, Ghana, Gabon, Gambia, Malawi). The study was part of a large multicentre prospective observational study of children admitted with falciparum malaria to SMAC (Severe Malaria in African Children clinical network). The prospective study aimed at setting up a core database to determine prognostic features in African children with severe malaria. It was the first study undertaken by the first clinical network devoted to the study of severe malaria in African children. A detailed description of the study design and participating sites was provided by Taylor T, Olola C, Valim C, et al. Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network. Trans R Soc Trop Med Hyg. 2006;100:615–22 and Olola CH, Missinou MA, Issifou S, et al. Medical informatics in medical research—the Severe Malaria in African Children (SMAC) Network's experience. Methods Inf Med. 2006;45:483–91. From December 2000 through May 2005, all children aged <1 to 180 months who were suspected of having malaria and were sick enough to be hospitalized were screened with a thick blood smear for the presence of P. falciparum parasitemia. Following consent from parents/guardians, children with positive blood smears were recruited into the study. The collection contains data on patient demographics, history of present illness, clinical details at the time of assessment and laboratory investigations.
Subject	Medicine, Health and Life Sciences
Related Publication	Taylor T, Olola C, Valim C, et al. Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network. Trans R Soc Trop Med Hyg. 2006;100:615–22doi: 10.1016/j.trstmh.2005.09.021
Notes	Terms of Access Access to the data file is restricted as it contains sensitive information on participants. For more detailed information beyond the metadata and documentation provided, there is a process of managed access requiring submission of a request form for consideration by our Data Governance Committee.
License/Data Use Agreement	Custom Dataset Terms

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	SMAC_Pigment_Codebook.pdf Adobe PDF - 43.7 KB Published Jan 24, 2020 24 Downloads MD5: 689a5bdd558da1471f23a3ef6972c4c5 Contains variable description and value labels DocumentationData Dictionary	Preview "SMAC_Pigment_Codebook.pdf" Access File File Access Public Download Options Adobe PDF Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	SMAC_Pigment_Codes.txt Plain Text - 4.3 KB Published Jan 24, 2020 0 Downloads MD5: 5219993878bc23cae467ad8c7f476cc1 Ethnic Group and Health Centre Codes Documentation	Access File File Access Restricted Users may not request access to files. Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	SMAC_Pigment_Procedure_Manual.pdf Adobe PDF - 111.8 KB Published Jan 24, 2020 14 Downloads MD5: 12fe6ac76426680d9a5734215494821a DocumentationManual of Procedures	Preview "SMAC_Pigment_Procedure_Manual.pdf" Access File File Access Public Download Options Adobe PDF Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	SMAC_Pigment_Readme.txt Plain Text - 5.8 KB Published Jan 24, 2020 11 Downloads MD5: 6613b4ae1ac360a90fff27afcb17a902 DocumentationReadme	Preview "SMAC_Pigment_Readme.txt" Access File File Access Public Download Options Plain Text Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	SMAC_Pigment_surveillance_redacted_CRF.pdf Adobe PDF - 44.2 KB Published Jan 24, 2020 12 Downloads MD5: f9af0906119f91a950d9b86c5c3b3742 DocumentationCase Report Form	Preview "SMAC_Pigment_surveillance_redacted_CRF.pdf" Access File File Access Public Download Options Adobe PDF Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	SMAC_Pigment_csv_files.zip ZIP Archive - 725.6 KB Published Jan 24, 2020 18 Downloads MD5: 97a33cb4faa3d9873d228473f5782313 Datacsv files	Preview "SMAC_Pigment_csv_files.zip" Access File File Access Public Download Options ZIP Archive Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	SMAC_Pigment Protocol R2001-04-05_NIH V2.pdf Adobe PDF - 573.2 KB Published Sep 23, 2020 16 Downloads MD5: a276e7874af18defc74371a4966d2b71 Study Protocol	Preview "SMAC_Pigment Protocol R2001-04-05_NIH V2.pdf" Access File File Access Public Download Options Adobe PDF Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX

Citation Metadata

Persistent Identifier	doi:10.7910/DVN/0CTWUJ
Publication Date	2020-01-24
Title	Data for: A multicenter, prospective observational study of intraleukocytic and intraerythrocytic pigment as prognostic features in African children with falciparum malaria
Author	Olola, ChristopherKenya Medical Research Institute for Geographic Medicine, Kilifi, Kenya Agbenyega, TsiriUniversity of Science and Technology, School of Medical Science, Kumasi, Ghana Kremsner, Peter GottfriedMedical Research Unit, Albert Schweitzer Hospital, Lambaréné; Department of Parasitology, Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany Newton, Charles R.Kenya Medical Research Institute for Geographic Medicine, Kilifi, Kenya Bojang, KalifaMedical Research Council Laboratories, Banjul, the Gambia Taylor, TerrieCollege of Osteopathic Medicine, Michigan State University, East Lansing, Michigan; Blantyre Malaria Project, University of Malawi College of Medicine, Blantyre, Malawi
Point of Contact	Use email button above to contact. Taylor, Terrie (College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan; Blantyre Malaria Project, University of Malawi College of Medicine, Blantyre, Malawi)
Description	This data collection was generated by a study of the prognostic significance of circulating pigment conducted by consortium of research units at five sites (Kenya, Ghana, Gabon, Gambia, Malawi). The study was part of a large multicentre prospective observational study of children admitted with falciparum malaria to SMAC (Severe Malaria in African Children clinical network). The prospective study aimed at setting up a core database to determine prognostic features in African children with severe malaria. It was the first study undertaken by the first clinical network devoted to the study of severe malaria in African children. A detailed description of the study design and participating sites was provided by Taylor T, Olola C, Valim C, et al. Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network. Trans R Soc Trop Med Hyg. 2006;100:615–22 and Olola CH, Missinou MA, Issifou S, et al. Medical informatics in medical research—the Severe Malaria in African Children (SMAC) Network's experience. Methods Inf Med. 2006;45:483–91. From December 2000 through May 2005, all children aged <1 to 180 months who were suspected of having malaria and were sick enough to be hospitalized were screened with a thick blood smear for the presence of P. falciparum parasitemia. Following consent from parents/guardians, children with positive blood smears were recruited into the study. The collection contains data on patient demographics, history of present illness, clinical details at the time of assessment and laboratory investigations.
Subject	Medicine, Health and Life Sciences
Related Publication	Taylor T, Olola C, Valim C, et al. Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network. Trans R Soc Trop Med Hyg. 2006;100:615–22 doi 10.1016/j.trstmh.2005.09.021 https://doi.org/10.1016/j.trstmh.2005.09.021 Olola CH, Missinou MA, Issifou S, et al. Medical informatics in medical research—the Severe Malaria in African Children (SMAC) Network's experience. Methods Inf Med. 2006;45:483–91. urn uuid:edd79265-4e5e-448f-b94b-bd44b5077371 https://ora.ox.ac.uk/objects/uuid:edd79265-4e5e-448f-b94b-bd44b5077371 Kremsner, Peter Gottfried, et al. "Prognostic value of circulating pigmented cells in African children with malaria." The Journal of infectious diseases 199.1 (2009): 142-150. doi 10.1086/595295 https://doi.org/10.1086/595295
Notes	Terms of Access Access to the data file is restricted as it contains sensitive information on participants. For more detailed information beyond the metadata and documentation provided, there is a process of managed access requiring submission of a request form for consideration by our Data Governance Committee.
Depositor	Taylor, Terrie
Deposit Date	2020-01-08

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Our Community Norms as well as good scientific practices expect that proper credit is given via citation. Please use the data citation shown on the dataset page.

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