Replication Data for: The impact of introducing the RTS,S/AS01E malaria vaccine delivered through routine immunization programmes on mortality in young children: 46-month evaluation of cluster-randomized deployment of the vaccine in Ghana, Kenya and Malawi

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Mwapasa, Victor; Asante, Kwaku Poku; Milligan, Paul; Akech, Samuel; ODURO, ABRAHAM; Mathanga, Don; Fogelson, Ari; Kwambai, Titus K; Hamel, Mary J; Kapito-Tembo, Atupele; Gyan, thomas; Westercamp, Nelli; Okine, Rafiq; Moore, Kerryn; Pellaux-Furrer E; Stanley, Christopher C.; Ansong, Daniel; Kariuki, Simon; Njuguna, Patricia; Mvalo, Tisungane; Welaga, Paul; Otienoc, Lucas; Snell, Paul; Schellenberg, David; Chimala, Alfred; Afari, Edwin; Bejon, Philip; Maleta, Kenneth; Agbenyega, Tsiri; Snow, Robert; Zulu, Madalitso D; Odei-Lartey, Eliezer; Chinkhumba, Jobiba; Samuels, Aaron; Malaria Vaccine Program Evaluation Partners, 2025, "Replication Data for: The impact of introducing the RTS,S/AS01E malaria vaccine delivered through routine immunization programmes on mortality in young children: 46-month evaluation of cluster-randomized deployment of the vaccine in Ghana, Kenya and Malawi", https://doi.org/10.7910/DVN/CONGVG, Harvard Dataverse, V1, UNF:6:DtHso3dqYTdRT17HBcH+qA== [fileUNF]

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Description	This is a replication dataset for the manuscript titled: "The impact of introducing the RTS,S/AS01E malaria vaccine delivered through routine immunization programmes on mortality in young children: 46-month evaluation of cluster-randomized deployment of the vaccine in Ghana, Kenya and Malawi."
Subject	Medicine, Health and Life Sciences
Notes	Data Access: Restricted Access to these data requires submission of a formal request for consideration by our Data Governance Committee. How to request Download and complete the data request form Email completed data request form to the Data Governance Committee at dgc@kemri-wellcome.org
License/Data Use Agreement	CC BY 4.0

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	1 to 10 of 12 Files	Original Format Archival Format (.tab)
	MVIP_M46_Variable_Codebook.xlsx MS Excel Spreadsheet - 25.8 KB Published Jun 17, 2025 4 Downloads MD5: 2301c330c856607316f456a20e4ef8f2 Contains variable descriptions and value labels DocumentationVariable Codebook/Data Dictionary	Access File File Access Public Download Options MS Excel Spreadsheet Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	cluster_list_all_coded_es-1.tab Tabular Data - 18.3 KB Published Jun 17, 2025 0 Downloads 5 Variables, 632 Observations UNF:6:WYZCPHU6nWoMnicN3AU36w== list of the clusters and sex/eligibility categories, in the mortality study DataStata (.dta)	Access File File Access Restricted Users may not request access to files. Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	cluster_list_all_coded_es.tab Tabular Data - 17.1 KB Published Jun 17, 2025 0 Downloads 5 Variables, 632 Observations UNF:6:WYZCPHU6nWoMnicN3AU36w== list of the clusters and sex/eligibility categories, in the mortality study DataStata (.dta)	Access File File Access Restricted Users may not request access to files. Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	cluster_list_hosp_coded_grp-1.tab Tabular Data - 4.2 KB Published Jun 17, 2025 0 Downloads 4 Variables, 154 Observations UNF:6:3i4Vs5PdZhyOndkdd/7fCw== list of the clusters and eligibility categories, for clusters in the sentinel hospital surveillance DataStata (.dta)	Access File File Access Restricted Users may not request access to files. Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	cluster_list_hosp_coded_grp.tab Tabular Data - 3.6 KB Published Jun 17, 2025 0 Downloads 4 Variables, 154 Observations UNF:6:3i4Vs5PdZhyOndkdd/7fCw== list of the clusters and eligibility categories, for clusters in the sentinel hospital surveillance Datacsv file	Access File File Access Restricted Users may not request access to files. Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	M46deaths_data.tab Tabular Data - 1.9 MB Published Jun 17, 2025 0 Downloads 22 Variables, 33546 Observations UNF:6:SlHxfPDuTFcvGvJEJqgDVw== contains the mortality data Datacsv file	Access File File Access Restricted Users may not request access to files. Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	M46hosp_data.tab Tabular Data - 4.1 MB Published Jun 17, 2025 0 Downloads 30 Variables, 58004 Observations UNF:6:qh98cBr1wPbwkc9Tuyj8Uw== contains the hospital admissions data Datacsv file	Access File File Access Restricted Users may not request access to files. Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	m46_deaths_archive.tab Tabular Data - 2.9 MB Published Jun 17, 2025 0 Downloads 22 Variables, 33546 Observations UNF:6:SlHxfPDuTFcvGvJEJqgDVw== DataStata (.dta)	Access File File Access Restricted Users may not request access to files. Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	m46_sentinel_archive.tab Tabular Data - 6.7 MB Published Jun 17, 2025 0 Downloads 30 Variables, 58004 Observations UNF:6:ILlsW8YKFv1nlHnpV5YmcQ== DataStata (.dta)	Access File File Access Restricted Users may not request access to files. Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	pm_m46_deaths_rr.do Stata Syntax - 4.7 KB Published Jun 17, 2025 2 Downloads MD5: cd6fd791a32a62c3c63cb9d975d4a8e9 generates the estimates of mortality rate ratios for each analysis population CodeSTATA do file	Preview "pm_m46_deaths_rr.do" Access File File Access Public Download Options Stata Syntax Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX

Citation Metadata

Persistent Identifier	doi:10.7910/DVN/CONGVG
Publication Date	2025-06-17
Title	Replication Data for: The impact of introducing the RTS,S/AS01E malaria vaccine delivered through routine immunization programmes on mortality in young children: 46-month evaluation of cluster-randomized deployment of the vaccine in Ghana, Kenya and Malawi
Author	School of Global and Public Health, Kamuzu University of Health Sciences, Blantyre, Malawihttps://orcid.org/0000-0002-2748-8902 Kintampo Health Research Centre, Research and Development Division, Ghana Health Service, Bono East Region, Ghanahttps://orcid.org/0000-0001-9158-351X Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdomhttps://orcid.org/0000-0003-3430-3395 Kenya Medical Research Institute-Wellcome Trust Research Programme, Nairobi, Kenyahttps://orcid.org/0000-0001-5126-1225 Navrongo Health Research Centre, Research and Development Division, Ghana Health Service, Ghanahttps://orcid.org/0000-0002-4191-7419 School of Global and Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi; Malaria Alert Centre, Kamuzu University of Health Sciences, Blantyre, Malawihttps://orcid.org/0000-0001-6816-1888 Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdomhttps://orcid.org/0000-0001-6928-9883 Malaria Branch, Division of Parasitic Diseases and Malaria, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Kisumu, Kenyahttps://orcid.org/0000-0003-1930-0911 Hamel, Mary JDepartment of Immunizations, Vaccines, and Biologicals, World Health Organization, Geneva, Switzerland School of Global and Public Health, Kamuzu University of Health Sciences, Blantyre, Malawihttps://orcid.org/0000-0001-8619-515X Kintampo Health Research Centre, Research and Development Division, Ghana Health Service, Bono East Region, Ghanahttps://orcid.org/0000-0003-2972-964X Malaria Branch, Division of Parasitic Diseases and Malaria, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USAhttps://orcid.org/0000-0003-0136-9750 Global Malaria Programme, World Health Organization, Geneva, Switzerlandhttps://orcid.org/0000-0002-9837-9172 London School of Hygiene and Tropical Medicine, London, United Kingdom; Murdoch Children’s Research Institute, Infection and Immunity, New Vaccines, Victoria, Australiahttps://orcid.org/0000-0002-8333-8271 Pellaux-Furrer EDepartment of Immunizations, Vaccines, and Biologicals, World Health Organization, Geneva, Switzerland Stanley, Christopher C.School of Global and Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi; Malaria Alert Centre, Kamuzu University of Health Sciences, Blantyre, Malawi Ansong, DanielAgogo Malaria Research Centre, Agogo, Ghana; Kwame Nkrumah University of Science and Technology, Ghana Kariuki, SimonCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya Njuguna, PatriciaGlobal Malaria Programme, World Health Organization, Geneva, Switzerland PATH Center for Vaccine Innovation and Access (CVIA) Nairobi, Kenya Mvalo, TisunganeUniversity of North Carolina Project-Malawi, Lilongwe, Malawi C. K Tedam University of Technology and Applied Sciences, Navrongo, Ghanahttps://orcid.org/0000-0002-0108-3384 Otienoc, LucasKenya Medical Research Institute-United States Army Medical Research Directorate-Africa, Kisumu, Kenya London School of Hygiene and Tropical Medicine, London, United Kingdomhttps://orcid.org/0000-0003-3917-617X Schellenberg, DavidGlobal Malaria Programme, World Health Organization, Geneva, Switzerland Chimala, AlfredMalaria Alert Centre, Kamuzu University of Health Sciences, Blantyre, Malawi School of Public Health, University of Ghana, Accra, Ghanahttps://orcid.org/0000-0002-3842-6037 Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdomhttps://orcid.org/0000-0002-2135-7549 Maleta, KennethSchool of Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi Agogo Malaria Research Centre, Agogo, Ghana; Kwame Nkrumah University of Science and Technology, Ghanahttps://orcid.org/0000-0002-6887-7728 Kenya Medical Research Institute-Wellcome Trust Research Programme, Nairobi, Kenya; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdomhttps://orcid.org/0000-0003-3725-6088 University of North Carolina Project-Malawi, Lilongwe, Malawihttps://orcid.org/0000-0002-6308-2627 Kintampo Health Research Centre, Research and Development Division, Ghana Health Service, Kintampo North Municipality, Ghanahttps://orcid.org/0000-0002-2074-9161 School of Global and Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi; Malaria Alert Centre, Kamuzu University of Health Sciences, Blantyre, Malawihttps://orcid.org/0000-0002-1921-619X Malaria Branch, Division of Parasitic Diseases and Malaria, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Kisumu, Kenya; Malaria Branch, Division of Parasitic Diseases and Malaria, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USAhttps://orcid.org/0000-0002-8355-8186 Malaria Vaccine Program Evaluation Partners
Point of Contact	Use email button above to contact. Snell, Paul (London School of Hygiene and Tropical Medicine, London, United Kingdom) The Data Governance Committee (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)
Description	This is a replication dataset for the manuscript titled: "The impact of introducing the RTS,S/AS01E malaria vaccine delivered through routine immunization programmes on mortality in young children: 46-month evaluation of cluster-randomized deployment of the vaccine in Ghana, Kenya and Malawi."
Subject	Medicine, Health and Life Sciences
Notes	Data Access: Restricted Access to these data requires submission of a formal request for consideration by our Data Governance Committee. How to request Download and complete the data request form Email completed data request form to the Data Governance Committee at dgc@kemri-wellcome.org
Language	English
Depositor	Snell, Paul
Deposit Date	2025-06-16
Data Type	Restricted Access

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