Persistent Identifier
|
doi:10.7910/DVN/LBSUYU |
Publication Date
|
2024-06-03 |
Title
| Replication Data for: Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro |
Author
| Nyagwange, JamesKEMRI-Wellcome Trust Research Programme, Kilifi, Kenya
Kutima, BernadetteKEMRI-Wellcome Trust Research Programme, Kilifi, Kenya
Mwai, KennedyKEMRI-Wellcome Trust Research Programme, Kilifi, Kenya |
Point of Contact
|
Use email button above to contact.
Nyagwange, James (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)
The Data Governance Committee (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
Description
| This is a replication dataset for the publication titled: "Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro."
The dataset used in this study included serum samples collected in 2018 in coastal Kenya from adults for malaria cross-sectional surveys, serum samples collected in 2020 Kenya-wide from adults investigated for SARS-CoV-2 infection.The prepandemic NP/OP samples were obtained from biobanked human NP/OP samples collected from study participants between 2015 and 2017 in the Kilifi Health and Demographic Surveillance System. The pandemic NP/OP samples set were SARS-CoV-2 RT-PCR test samples performed at the KEMRI-CGMRC between March and July 2020. Both sera and NP/OP before and during the COVID-19 pandemic provided the basis for comparison of immune responses between the two periods. |
Subject
| Medicine, Health and Life Sciences |
Keyword
| SARS-CoV-2
Human coronaviruses
Pre-existing antibodies
Spike proteins |
Related Publication
| Nyagwange, J., Kutima, B., Mwai, K., Karanja, H.K., Gitonga, J.N., Mugo, D., Sein, Y., Wright, D., Omuoyo, D.O., Nyiro, J.U. and Tuju, J., 2023. Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro. International Journal of Infectious Diseases, 127, pp.11-16. doi 10.1016/j.ijid.2022.11.041 https://www.ijidonline.com/article/S1201-9712(22)00633-6/fulltext#articleInformation |
Notes
| Data Availability
Access to these data requires submission of a formal request for consideration by our Data Governance Committee. How to request
- Download and complete the data request form
- Email completed data request form to the Data Governance Committee at dgc@kemri-wellcome.org
|
Depositor
| Nyagwange, James |
Deposit Date
| 2024-05-28 |
Data Type
| Restricted Access |