Replication Data for: Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi

Version 4.1

Asante, Kwaku Poku; Oduro, Abraham; Welega,Paul; Ansong, Daniel; Odei-Lartey, Eliezer; Gyan, Thomas; Gyaase, Stephaney; Sarfo, Augustine; Samuels, Aaron; Westercamp, Nelli; Akech, Samuel; Kwambai, Titus; Khazenzi, Cynthia; Milligan, Paul; Snell, Paul; Moore, Kerryn; Fogelson, Ari; Schellenberg, David; Hamel, Mary; Okine, Rafiq; Mathanga, Don; Mwapasa, Victor; Kapito, Atupele; Mvalo, Tisungane; Msuku, Harrison; Stanley, Christopher; Njuguna, patricia; Kariuki, Simon; Otieno, Lucas; Chimala, Alfred; Afari, Edwin A.; Bejon, Philip; Maleta, Kenneth; Agbenyega, Tsiri; Snow, Robert W.; Zulu, Madaliso; Chinkhumba, Jobiba; Chinkumba, Jobiba; Abubakari, Sulemana Watara; Akumani, Albert; Adu-Gyasi, Dennis; Agbokey, Francis; Amenga-Etego, Seeba; Buabeng, Patrick; Awini, Elizabeth; Sylverken, Justice; Kampim, Aaron; Koram, Kwadwo A .; Hodgson, Abraham; Binka, Fred N.; Tweneboah, Peter Ofori; Ondiegi, Bella; Seda, Brian; Akach, Dorcas; Orwa, Gordon; Nyang’au, Isabella; Odunga, Oscar; Gumba, Francis; Copeland, Nathanial; Mumo, Eda; Musa, Monica; English, Mike; Haji, Adam; Njoroge, Josephine; Msuku, Harrison; Samuel, Vincent; Mariko, Hillary Topazian; Juliano, Jon; Msumba, Lusungu; Mungwira, Randy George; Zimba, Boston Edward; Desai, Meghna; Furrer, Eliane; Aponte, John; Alonso, Pedro; Sillah, Jackson Sophianu; Kalu, Akpaka A., 2024, "Replication Data for: Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi", https://doi.org/10.7910/DVN/VOZU4T, Harvard Dataverse, V4, UNF:6:/+G0PtDyx5s/wAy7F34XMg== [fileUNF]

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Description	This is a replication dataset for the research publication titled: "Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi."
Subject	Medicine, Health and Life Sciences
Related Publication	Asante, Kwaku Poku, Don P. Mathanga, Paul Milligan, Samuel Akech, Abraham Oduro, Victor Mwapasa, Kerryn A. Moore et al. "Feasibility, safety, and impact of the RTS, S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi." The Lancet 403, no. 10437 (2024): 1660-1670.doi: 10.1016/S0140-6736(24)00004-7
Notes	Data Access: Restricted Access to these data requires submission of a formal request for consideration by our Data Governance Committee. How to request Download and complete the data request form Email completed data request form to the Data Governance Committee at dgc@kemri-wellcome.org
License/Data Use Agreement	CC BY 4.0

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	M24_dataset_readme.ro13.5.2024.txt Plain Text - 8.3 KB Published May 13, 2024 22 Downloads MD5: c41142239fb151a4983158f2b0407251 DocumentationReadme	Preview "M24_dataset_readme.ro13.5.2024.txt" Access File File Access Public Download Options Plain Text Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	MVIP_M24_Data Dictionary.pdf Adobe PDF - 217.3 KB Published May 13, 2024 25 Downloads MD5: 24bf4e24fa5d787bd53f581e57ffc943 DocumentationVariable Codebook/Data Dictionary	Preview "MVIP_M24_Data Dictionary.pdf" Access File File Access Public Download Options Adobe PDF Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	MVIP_M24_Data Dictionary.xlsx MS Excel Spreadsheet - 26.9 KB Published May 13, 2024 23 Downloads MD5: e4d927e55ddc3879ec70ab47174289a8 DocumentationVariable Codebook/Data Dictionary	Access File File Access Public Download Options MS Excel Spreadsheet Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	cluster_list_all_coded_es.tab Tabular Data - 17.1 KB Published May 13, 2024 2 Downloads 5 Variables, 632 Observations UNF:6:IyM+ARa8+wLVjf+5+XhCTw== List of all cluster/eligibility/sex combinations (used to assign zero counts to those cluster/eligibility/sex categories that did not report any deaths) Data.csv	Access File File Access Restricted Request Access Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	cluster_list_hosp_coded_e.tab Tabular Data - 3.6 KB Published May 13, 2024 2 Downloads 4 Variables, 154 Observations UNF:6:+pQzY7MPgoawwYQgIjpikA== List of all cluster/eligibility combinations (used to assign zero counts for an outcome to those cluster/eligibility categories that did not report any events for that outcome) Data.csv	Access File File Access Restricted Request Access Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	M24deaths_data.tab Tabular Data - 455.7 KB Published May 13, 2024 3 Downloads 8 Variables, 14609 Observations UNF:6:4DWPk51+n/Bw8+IRWNHOuQ== List of deaths that occurred from vaccine introduction until 30/Apr/2021 Data.csv	Access File File Access Restricted Request Access Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	M24hosp_data.tab Tabular Data - 1.2 MB Published May 13, 2024 2 Downloads 18 Variables, 27678 Observations UNF:6:YpH/o6Vm8RYTPiXRX/P5LA== List of all hospital admissions and any outcomes of interest from vaccine introduction until 30/Apr/2021 Data.csv	Access File File Access Restricted Request Access Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	mvip_m24_baseline.tab Tabular Data - 908.5 KB Published Jan 22, 2025 2 Downloads 16 Variables, 17512 Observations UNF:6:aiVorUshbvUqZfvZYbdidQ== Data.csv	Access File File Access Restricted Request Access Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	mvip_m24_midline.tab Tabular Data - 1.1 MB Published Jan 22, 2025 3 Downloads 25 Variables, 17791 Observations UNF:6:uStsfjF7oOtOhXKiKfF3hw== Data.csv	Access File File Access Restricted Request Access Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX
	pmrrhosp24.do Stata Syntax - 4.9 KB Published May 13, 2024 18 Downloads MD5: 9ba7357ad5299a8f0aebb2648ac4d05e Stata DO file that calculates rate ratios and tests of homogeneity for hospital outcomes CodeSTATA do file	Preview "pmrrhosp24.do" Access File File Access Public Download Options Stata Syntax Download Metadata Data File Citation Download EndNote XML Download RIS Download BibTeX

Citation Metadata

Persistent Identifier	doi:10.7910/DVN/VOZU4T
Publication Date	2024-05-13
Title	Replication Data for: Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi
Author	Asante, Kwaku PokuKintampo Health Research Centre Oduro, AbrahamGhana Health Service Welega,PaulNavrongo Health Reserch Centre Ansong, DanielKomfo Anokye Teaching Hospital Odei-Lartey, EliezerKintampo Health Research Centre Gyan, ThomasKintampo Health Research Centre Gyaase, StephaneyKintampo Health Research Centre Sarfo, AugustineKintampo Health Research Centre Samuels, AaronUS Centers for Disease Control and Prevention, Pretoria, South Africa Westercamp, NelliUS Centers for Disease Control and Prevention, Pretoria, South Africa Akech, SamuelUS Centers for Disease Control and Prevention, Pretoria, South Africa Kwambai, TitusUS Centers for Disease Control and Prevention, Pretoria, South Africa Khazenzi, CynthiaKEMRI-Wellcome Trust Research Programme Milligan, PaulLondon School of Hygiene and Tropical Medicine Snell, PaulLondon School of Hygiene and Tropical Medicine Moore, KerrynMurdoch Children’s Research Institute, Infection and Immunity, New Vaccines, Parkville, VIC, Australia Fogelson, AriLondon School of Hygiene and Tropical Medicine Schellenberg, DavidLondon School of Hygiene and Tropical Medicine Hamel, MaryWorld Health Organization Okine, RafiqWorld Health Organization Mathanga, DonKamuzu University of Health Sciences (KUHeS) Mwapasa, VictorKamuzu University of Health Sciences (KUHeS) Kapito, AtupeleKamuzu University of Health Sciences (KUHeS) Mvalo, TisunganeUNC Project, Malawi Msuku, HarrisonKamuzu University of Health Sciences (KUHeS) Stanley, ChristopherKamuzu University of Health Sciences (KUHeS) Njuguna, patriciaGlobal Malaria Programme, WHO, Geneva, Switzerland Kariuki, SimonCentre for Global Health Research, KEMRI, Kisumu, Kenya Otieno, LucasKEMRI–US Army Medical Research Directorate-Africa, Kisumu, Kenya Chimala, AlfredMalaria Alert Centre, Kamuzu University of Health Sciences, Blantyre, Malawi Afari, Edwin A.School of Public Health, University of Ghana, Accra, Ghana Bejon, PhilipKenya Medical Research Institute (KEMRI)–Wellcome Trust Research Programme, Nairobi, Kenya Maleta, KennethSchool of Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi Agbenyega, TsiriAgogo Malaria Research Centre, Agogo, Ghana; Kwame Nkrumah University of Science and Technology, Kumasi, Ghana Snow, Robert W.Kenya Medical Research Institute (KEMRI)–Wellcome Trust Research Programme, Nairobi, Kenya Zulu, MadalisoUniversity of North Carolina Project-Malawi, Lilongwe, Malawi Chinkhumba, JobibaSchool of Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi Chinkumba, JobibaMalaria Vaccine Programme Evaluation Partners Abubakari, Sulemana WataraMalaria Vaccine Programme Evaluation Partners Akumani, AlbertMalaria Vaccine Programme Evaluation Partners Adu-Gyasi, DennisMalaria Vaccine Programme Evaluation Partners Agbokey, FrancisMalaria Vaccine Programme Evaluation Partners Amenga-Etego, SeebaMalaria Vaccine Programme Evaluation Partners Buabeng, PatrickMalaria Vaccine Programme Evaluation Partners Awini, ElizabethMalaria Vaccine Programme Evaluation Partners Sylverken, JusticeMalaria Vaccine Programme Evaluation Partners Kampim, AaronMalaria Vaccine Programme Evaluation Partners Koram, Kwadwo A .Malaria Vaccine Programme Evaluation Partners Hodgson, AbrahamMalaria Vaccine Programme Evaluation Partners Binka, Fred N.Malaria Vaccine Programme Evaluation Partners Tweneboah, Peter OforiMalaria Vaccine Programme Evaluation Partners Ondiegi, BellaMalaria Vaccine Programme Evaluation Partners Seda, BrianMalaria Vaccine Programme Evaluation Partners Akach, DorcasMalaria Vaccine Programme Evaluation Partners Orwa, GordonMalaria Vaccine Programme Evaluation Partners Nyang’au, IsabellaMalaria Vaccine Programme Evaluation Partners Odunga, OscarMalaria Vaccine Programme Evaluation Partners Gumba, FrancisMalaria Vaccine Programme Evaluation Partners Copeland, NathanialMalaria Vaccine Programme Evaluation Partners Mumo, EdaMalaria Vaccine Programme Evaluation Partners Musa, MonicaMalaria Vaccine Programme Evaluation Partners English, MikeMalaria Vaccine Programme Evaluation Partners Haji, AdamMalaria Vaccine Programme Evaluation Partners Njoroge, JosephineMalaria Vaccine Programme Evaluation Partners Msuku, HarrisonMalaria Vaccine Programme Evaluation Partners Samuel, VincentMalaria Vaccine Programme Evaluation Partners Mariko, Hillary TopazianMalaria Vaccine Programme Evaluation Partners Juliano, JonMalaria Vaccine Programme Evaluation Partners Msumba, LusunguMalaria Vaccine Programme Evaluation Partners Mungwira, Randy GeorgeMalaria Vaccine Programme Evaluation Partners Zimba, Boston EdwardMalaria Vaccine Programme Evaluation Partners Desai, MeghnaMalaria Vaccine Programme Evaluation Partners Furrer, ElianeMalaria Vaccine Programme Evaluation Partners Aponte, JohnMalaria Vaccine Programme Evaluation Partners Alonso, PedroMalaria Vaccine Programme Evaluation Partners Sillah, Jackson SophianuMalaria Vaccine Programme Evaluation Partners Kalu, Akpaka A.Malaria Vaccine Programme Evaluation Partners
Point of Contact	Use email button above to contact. Asante, Kwaku Poku (Kintampo Health Research Centre ) Samuels, Aaron (US Centers for Disease Control and Prevention, Pretoria, South Africa) Mathanga, Don (Kamuzu University of Health Sciences (KUHeS)) Snell, Paul (London School of Hygiene and Tropical Medicine) Milligan, Paul (School of Hygiene & Tropical Medicine, London WC1E 7HT, UK) Moore, Kerryn (Murdoch Children’s Research Institute, Infection and Immunity, New Vaccines, Parkville, VIC, Australia) Fogelson, Ari (London School of Hygiene and Tropical Medicine) Hamel , Mary (World Health Organization) Okine, Rafiq (World Health Organization) The Data Governance Committee (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya)
Description	This is a replication dataset for the research publication titled: "Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi."
Subject	Medicine, Health and Life Sciences
Related Publication	Asante, Kwaku Poku, Don P. Mathanga, Paul Milligan, Samuel Akech, Abraham Oduro, Victor Mwapasa, Kerryn A. Moore et al. "Feasibility, safety, and impact of the RTS, S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi." The Lancet 403, no. 10437 (2024): 1660-1670. doi 10.1016/S0140-6736(24)00004-7 https://doi.org/10.1016/S0140-6736(24)00004-7
Notes	Data Access: Restricted Access to these data requires submission of a formal request for consideration by our Data Governance Committee. How to request Download and complete the data request form Email completed data request form to the Data Governance Committee at dgc@kemri-wellcome.org
Depositor	Snell, Paul
Deposit Date	2024-04-30

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