Replication Data for: A field bioassay for assessing ivermectin bio-efficacy in wild malaria

Version 2.0
Replication Data for: A field bioassay for assessing ivermectin bio-efficacy in wild malaria
Ominde, Kelly M.; Kamau, Yvonne; Karisa, Jonathan; Muturi, Martha N.; Kiuru, Caroline; Wanjiku, Caroline; Babu, Lawrence; Yaah, Festus; Tuwei, Mercy; Musani, Haron; Ondieki, Zedekiah; Muriu, Simon; Mwangangi, Joseph; Maia, Marta F., 2023, "Replication Data for: A field bioassay for assessing ivermectin bio-efficacy in wild malaria", https://doi.org/10.7910/DVN/YYUKHF, Harvard Dataverse, V2, UNF:6:CFC+etNXifMwJmKNlpTWtg== [fileUNF]
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Description

This is a replication dataset for the manuscript titled: "A field bioassay for assessing ivermectin bio-efficacy in wild malaria."

The files contain survival dataset for insectary cohort mosquitoes exposed to different concentrations of ivermectin and followed up for 28 days including wild mosquitoes followed up for 14 days post exposure as well. The nature of data is binnary and data was collected by recording 0 for no mortality and 1 for each individual mortality event. The goal was to determine mosquitocidal effect of ivermectin administered in sugar alone compared to blood and later administered in different mixtures of blood and sugar mixtures with an aim of developing a field friendly bioassay for assessing ivermectin bio-efficacy in wild malaria vectors. The different datasets are grouped as ivermectin spiked in sugar (glucose solution), ivermectin spiked in blood, ivermectin spiked in different mixtures of blood and glucose solution of varying ratios (Blood to sugar) 1:1, 1:2, 1:4 and 1:8. Mealsize estimation file contains dataset for individual mosquito weights (in milligrams) obtained after being fed on either: 1) blood; 2) glucose solution; 3) 1:1 blood to glucose mixture; 4) 1:2 blood to glucose mixture; 5) 1:4 blood to glucose mixture; or 6) 1:8 blood to glucose mixtures. Species ID by morphology and PCR are dataset for the wild mosquitoes identified to species complex by microscopy and at sibling species molecularly by PCR methods respectively.

Subject Medicine, Health and Life Sciences
Keyword Ivermectin, monitoring, vector control, bio-efficacy, Anopheles gambiae, Kenya, field bioassay, wild vectors
Notes

Data Access: Open

Data Citation Requirements: All outputs based on this data collection should acknowledge this source by means of bibliographic citation

License/Data Use Agreement

CC BY 4.0

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KOminde_ivermectin_bioefficacy_data_codebook.pdf
KOminde_ivermectin_bioefficacy_data_codebook.pdf
Adobe PDF - 222.8 KB
Published Mar 7, 2023
3 Downloads
MD5: dc2d460bed8b0a1a34404c1755898d60
DocumentationVariable Codebook/Data Dictionary
Preview "KOminde_ivermectin_bioefficacy_data_codebook.pdf"
KOminde_ivermectin_bioefficacy_data_readme.txt
Plain Text - 7.3 KB
Published Mar 7, 2023
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MD5: db04c7872d98ef2a17bee4f619e7ce15
DocumentationReadme
Preview "KOminde_ivermectin_bioefficacy_data_readme.txt"
B S 1 to 1.tab
Tabular Data - 17.5 KB
Published Mar 7, 2023
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5 Variables, 872 Observations UNF:6:59mSXcpkfSAwxif7rtUd/g==
Datacsv
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B S 1 to 2.tab
Tabular Data - 16.6 KB
Published Mar 7, 2023
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5 Variables, 830 Observations UNF:6:SMstiMrUe+Cua+jIxFyAnQ==
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B S 1 to 4.tab
Tabular Data - 18.4 KB
Published Mar 7, 2023
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5 Variables, 922 Observations UNF:6:g20x/cdqpTwZsCc5OskqbA==
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B S 1 to 4_wildmozzie.tab
Tabular Data - 12.0 KB
Published Mar 7, 2023
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5 Variables, 598 Observations UNF:6:Zp1DdbOVTAqU9ORrMB9E3A==
Datacsv
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B S 1 to 8.tab
Tabular Data - 18.1 KB
Published Mar 7, 2023
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5 Variables, 894 Observations UNF:6:JqJzD34PosGLqeRwMOmvOg==
Datacsv
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IVM_spiked_blood.tab
Tabular Data - 16.2 KB
Published Mar 7, 2023
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5 Variables, 815 Observations UNF:6:W5Cql0JPHKFfpuq1HLK5xw==
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IVM_spiked_sugar.tab
Tabular Data - 18.3 KB
Published Mar 7, 2023
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5 Variables, 906 Observations UNF:6:MrUTc9uyJX9r0Ug087+VTw==
Datacsv
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Meal size estimation IVM Bioefficacy.xlsx
MS Excel Spreadsheet - 10.7 KB
Published Mar 7, 2023
3 Downloads
MD5: d8803eec4ebab2eeafa4f0c058dbeb36
Datacsv
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