We have had a major input in evaluating the effectiveness and wider impact of the pneumococcal conjugate vaccine (PCV10) in Kenya, including studies of the effect on carriage, invasive disease, burden of pneumonia and pathogen structure. We are expanding our platform of surveillance to incorporate assessments of the safety of EPI vaccines, direct and indirect effects of rotavirus vaccination, and studies of the non-specific effects of vaccination. We will examine the epidemiology of invasive salmonella infection and salmonella carriage in children and adults, and participate in the clinical development of a whole cell pneumococcal vaccine which is serotype independent.

The group is affiliated to the Kemri Wellcome Trust Research Programme and Wellcome Trust. Each dataset has a citation and DOI, facilitating attribution and connection to research publications. For information about the IBD Data Archive, please visit our website http://pcvis.org .

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11 to 17 of 17 Results
Feb 8, 2021
Adetifa, Ifedayo M.O.; Uyoga, Sophie; Gitonga, John N.; Otiende, Mark; Nyagwange, James; Karanja, Henry K.; Tuju, James; Wanjiku, Perpetual; Aman, Rashid; Mwangangi, Mercy; Amoth, Patrick; Kasera, Kadondi; Ng’ang’a, Wangari; Rombo, Charles; Yegon, Christine; Kithi, Khamisi; Odhiambo, Elizabeth; Rotich, Thomas; Orgut, Irene; Kihara, Sammy; Bottomley, Christian; Kagucia, Eunice W.; Gallagher, Katherine E.; Etyang, Anthony; Voller, Shirine; Lambe, Teresa; Wright, Daniel; Barasa, Edwine; Tsofa, Benjamin; Bejon, Philip; Ochola-Oyier, Lynette I.; Agweyu, Ambrose; Scott, J. Anthony G.; Warimwe, George M., 2021, "Replication Data for: Temporal trends of SARS-CoV-2 seroprevalence in transfusion blood donors during the first wave of the COVID-19 epidemic in Kenya", https://doi.org/10.7910/DVN/FQUNVD, Harvard Dataverse, V1, UNF:6:ItlGSwhwfrDEH/48aUySlA== [fileUNF]
This is a replication dataset for the manuscriot titled: "Temporal trends of SARS-CoV-2 seroprevalence in transfusion blood donors during the first wave of the COVID-19 epidemic in Kenya". These data contain anonymised residual donor serum samples used for screening of transfusion transmissible infections were collected at the KNBTS regional centre...
Mar 11, 2020
Odipo, Emily; Sigilai, Antipa; Etyang, Anthony O., 2020, "Replication Data for: Diagnostic Accuracy of Unattended Automated Office Blood Pressure Measurement in Screening for Hypertension in Kenya", https://doi.org/10.7910/DVN/AAIKJ4, Harvard Dataverse, V1, UNF:6:5ZmpJ7jw2ImmjYlkgGfBEg== [fileUNF]
This a replication dataset for the paper Etyang, A.O., Sigilai, A., Odipo, E., Oyando, R., Ong’ayo, G., Muthami, L., Munge, K., Kirui, F., Mbui, J., Bukania, Z. and Mwai, J., 2019. Diagnostic accuracy of unattended automated office blood pressure measurement in screening for hypertension in Kenya. Hypertension, 74(6), pp.1490-149. doi:https://doi.o...
Feb 20, 2020
Seeley, Anna, 2020, "Replication Data for: Systematic review and meta-analysis for hypertension treatment in Sub-Saharan Africa.", https://doi.org/10.7910/DVN/ZZRWOM, Harvard Dataverse, V1, UNF:6:Zwqu4pwKCQguybqu+tnjEw== [fileUNF]
This dataset holds summary data extracted from the 32 papers included in our systematic review. Titles were chosen based on results from systematic search across 4 databases and on our inclusion criteria, published in the accompanying manuscript. Data quality were assessed using the Cochrane Risk of Bias tool. Data was extracted twice, first into s...
Feb 20, 2020
Morpeth, Susan C.; Ngure, Kagia; Scott, J. Anthony G., 2020, "Replication Data for: Carriage and acquisition of Extended Spectrum Beta-Lactamase producing Enterobacterales among neonates admitted to hospital in Kilifi, Kenya", https://doi.org/10.7910/DVN/E8HR7I, Harvard Dataverse, V1, UNF:6:8UZ9sl0WnFQiTiFoxz7pcQ== [fileUNF]
Infections caused by extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) among hospitalized neonates in sub-Saharan Africa pose significant clinical challenges. In a cohort study of consecutive neonatal admissions to Kilifi County Hospital (KCH) from July 2013-August 2014, we estimated ESBL-E carriage prevalence on admission using...
Jul 9, 2018
Ominde, Micah Silaba; Scott, J. Anthony G., 2018, "Replication Data for: Reliability and validity of the World Health Organization reading standards for paediatric chest radiographs used in the field in an impact study of Pneumococcal Conjugate Vaccine in Kilifi, Kenya", https://doi.org/10.7910/DVN/WYAPHO, Harvard Dataverse, V1, UNF:6:wqCpN9/zbXViti9v6CMMrg== [fileUNF]
Radiologically-confirmed pneumonia (RCP) is a specific end-point used in trials of Pneumococcal Conjugate Vaccine (PCV) to estimate vaccine efficacy. The dataset is for a study which was set up to ascertain repeatability and reliability of paediatric chest radiographs(CXR) interpretation using percent agreement and Cohen’s kappa in a study of the i...
Apr 23, 2018
Etyang, A.O., 2018, "Replication Data for: Blood Pressure and Arterial Stiffness in Kenyan Adolescents With α+Thalassemia", https://doi.org/10.7910/DVN/0GTMAN, Harvard Dataverse, V1, UNF:6:/3s3KxvPr1NGrcI7F55NcA== [fileUNF]
Background recent studies have discovered that a_globin is expressed in blood vessel walls where it plays a role in regulating vascular tone. We tested the hypothesis that blood pressure (BP) might differ between normal individuals and those with alpha thalassemia, in whom the production of alpha globin is reduced. The related study - Shinikizo la...
Jan 27, 2017
Kazungu, Jacob S.; Adetifa, Ifedayo, 2017, "Replication Data for: Crude childhood vaccination coverage in West Africa: trends and predictors of completeness", https://doi.org/10.7910/DVN/YQYES9, Harvard Dataverse, V2
Africa currently has the lowest childhood vaccination coverage worldwide. If the full benefits of childhood vaccination programmes are to be enjoyed in sub-Saharan Africa, all countries need to improve on delivery of vaccines to achieve and sustain high coverage. In this paper, we reviewed trends in vaccination coverage, dropouts rates and explored...
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