The Childhood Acute Illness and Nutrition Network (CHAIN) is a global research network focused on optimizing the management and care of highly vulnerable children in resource-limited settings to improve survival, growth and development.

The CHAIN Network aims to identify the biological mechanisms and the socio-economic factors that determine a child’s risk of mortality in the six months following presentation to medical care with an acute illness. Ultimately, The CHAIN Network aims to improve care for acutely ill children living in countries with limited resources and prevent both in-hospital and post-discharge mortality. To do this, the progress of acutely ill children across a range of nutritional status will be tracked throughout their hospital stay and for 6 months after returning to their home and communities. This research will guide the choice of strategies to be taken forth into clinical trials to reduce mortality in this highly vulnerable population.

Read more about the CHAIN Network from our website here

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11 to 20 of 30 Results
ICF.zip
Jun 13, 2024 - Data for: Pancreatic Enzymes and Bile Acids: A Non-Antibiotic approach to Treat Intestinal Dysbiosis in Acutely Ill Severely Malnourished Children
ZIP Archive - 842.4 KB - MD5: 53c368e817c7d41be3ac695e8a87f763
Protocol.zip
Jun 13, 2024 - Data for: Pancreatic Enzymes and Bile Acids: A Non-Antibiotic approach to Treat Intestinal Dysbiosis in Acutely Ill Severely Malnourished Children
ZIP Archive - 1.5 MB - MD5: 8ddf882aaa1a7a231b136e51571eb384
raw_data.zip
Jun 13, 2024 - Data for: Pancreatic Enzymes and Bile Acids: A Non-Antibiotic approach to Treat Intestinal Dysbiosis in Acutely Ill Severely Malnourished Children
ZIP Archive - 2.1 MB - MD5: 917076bf4b461afb98f131bbbaadb4ab
Data
Readme.txt
Jun 13, 2024 - Data for: Pancreatic Enzymes and Bile Acids: A Non-Antibiotic approach to Treat Intestinal Dysbiosis in Acutely Ill Severely Malnourished Children
Plain Text - 8.3 KB - MD5: 21301977802d2ea8006a3849e9164409
DocumentationReadme
Study Questionnaires_CRFs.zip
Jun 13, 2024 - Data for: Pancreatic Enzymes and Bile Acids: A Non-Antibiotic approach to Treat Intestinal Dysbiosis in Acutely Ill Severely Malnourished Children
ZIP Archive - 5.0 MB - MD5: 0eec78a59ca6e8c5d09d8ce93d1cb719
PB-SAM_SAP_Final.docx.pdf
Jan 11, 2024 - Data for: Pancreatic Enzymes and Bile Acids: A Non-Antibiotic approach to Treat Intestinal Dysbiosis in Acutely Ill Severely Malnourished Children
Adobe PDF - 1.3 MB - MD5: 8b4ce8ea539247898403dee26921b232
Data for: CHAIN neurodevelopment sub-study
Jul 7, 2022
van den Heuvel, Meta, 2022, "Data for: CHAIN neurodevelopment sub-study", https://doi.org/10.7910/DVN/VYJEJK, Harvard Dataverse, V1
The dataset contains all data used to analyze the neurodevelopment sub-study that was run between 01/01/2017 and 01/01/2019. This was a multi-site longitudinal study that involved 3 sites in 3 countries. The study compared antibiotic used to treat children with severe acute malnutrition.Participant demographic, clinical, social, and laboratory data...
CHAIN_NeuroDevelopment_database_2022-07-06.csv
Jul 7, 2022 - Data for: CHAIN neurodevelopment sub-study
Comma Separated Values - 484.8 KB - MD5: 3bc9ca470475833b35209593a08dca26
CSVData
Contains all data used for neurodevelopment sub-study
CHAIN_neurodevelopment_DATA_Readme.txt
Jul 7, 2022 - Data for: CHAIN neurodevelopment sub-study
Plain Text - 3.5 KB - MD5: 747c33e740c7ef10c9b583a77d239a78
DocumentationReadme
Data for: Childhood Acute Illness and Nutrition (CHAIN) Network: a multi-site prospective cohort study to identify modifiable risk factors for mortality among acutely ill children in Africa and Asia
Data for: Childhood Acute Illness and Nutrition (CHAIN) Network: a multi-site prospective cohort study to identify modifiable risk factors for mortality among acutely ill children in Africa and Asia
Jan 28, 2021 - Clinical Research
The Childhood Acute Illness and Nutrition Network, 2021, "Data for: Childhood Acute Illness and Nutrition (CHAIN) Network: a multi-site prospective cohort study to identify modifiable risk factors for mortality among acutely ill children in Africa and Asia", https://doi.org/10.7910/DVN/5H5X0P, Harvard Dataverse, V1, UNF:6:6hItf/nkz0vCQ+cljRC6fw== [fileUNF]
This dataset contains the entire data that was collected by the CHAIN prospective cohort study that was run between 01/11/2016 and 31/03/2019. The study was a multi-site longitudinal study that involved 9 sites in 6 countries. During the study, participant demographic, clinical, social, GPS and laboratory data was collected at various timepoints de...
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