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Sep 15, 2023
Sang, Samuel; Datoo, Mehreen; Otieno, Edward; Muiruri, Charles; Gathuri, Emmaloise; Ngoto,Omar; Musembi, Janet; Bellamy, Duncan; Provstgaard-Morys, Samuel; Stockdale, Lisa; Aboagye, Jeremy; Woods, Daniel; Lawrie, Alison; Roberts, Rachel; Keter, Kelvias; Kimani, Domtila; Ndungu, Francis; Kapulu, Melissa; Njau, Irene; Orindi, Benedict; Ewer, Katie; Hill, Adrian V. S.; Bejon, Philip; Hamaluba, Mainga, 2023, "Data for: A Phase 1b, open-label, age de-escalation, dose-escalation study to evaluate the safety and immunogenicity of different doses of a candidate malaria vaccine; adjuvanted R21(R21/MM) in adults, young children and infants in Kilifi, Kenya", https://doi.org/10.7910/DVN/IRGZ35, Harvard Dataverse, V5, UNF:6:8VbuHGi8Xr05EETTLqzF9g== [fileUNF]
In the era of anti-malaria drug resistance and resistance to insecticide treated bed nets, there is an urgent need for a highly efficacious vaccine. We evaluated a candidate malaria vaccine incorporating the antigen R21 (part of the P. falciparum circumsporozoite malaria antigen co-expressed with hepatitis B antigen plus an adjuvant to boost the im... |
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