This Dataverse contains supplemental datasets of publications by Ran lab. We focus on the role of bone marrow derived myeloid lymphatic endothelial cells in promoting lymphatic vasculature through fusion with lymphatic endothelial cells of breast tumors.
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JPEG Image - 218.7 KB - MD5: 6ca345eaea6dfdfa0d932cf58f664e1f
Figure 6 ~295 um long Lyve-1 positive vessel co-expressing CD11b in EMT6 tumors- Panel A
JPEG Image - 131.2 KB - MD5: 4d17b953959169d8fb2f118f3215a729
Figure 5 Merged image showing complete overlap in GFP and mCherry expression and multinucleation in hybrids- Panel F
JPEG Image - 117.1 KB - MD5: fbf72e4d86d3b6b1ede68f74cb79294c
Merged image showing CD36/Lyve-1 double positive cells in MDA-MB-231 tumors - Figure 3 Panel C
JPEG Image - 98.7 KB - MD5: 0cfa02759523d99733dbafc7c508a79a
Merged image showing Dap12/Lyve-1 double positive cells in MDA-MB-231 tumors- Panel E
JPEG Image - 235.6 KB - MD5: aa9e6cfddee81991e0ff40f37abb46db
Figure 6 Merged image showing multiple bone marrow derived Y chromosome in the lymphatic endothelial monolayer and associated multinucleation in EMT6 tumors -Panel B
JPEG Image - 96.0 KB - MD5: 259c42b5be79bf708e29e2910b9d9784
Figure 8 Merged image for Panels A and C showing nuclear integrated Y chromosome; high expression of proliferation marker Acetyl at fork of new blood vessel sprouts
JPEG Image - 119.3 KB - MD5: 490d7d66788269f78b9c2cd87394ef88
Merged image showing Sirp-a/Lyve-1 double positive cells in MDA-MB-231 tumors - Figure 3; Panel A
MS Excel Spreadsheet - 26.1 KB - MD5: 37957a83b4f781e1fbe19ca04c110f80
Raw data for Figure 1 and 2 of manuscript demonstrating CT values of fusogenic regulators in mouse and human undifferentiated and Th2 differentiated bone marrow cells; percent positive cells and MFI for fusogenic proteins in ex vivo, CSF-1 only, CSF-1 + LPS/IL-4/IL-10 treated mouse BM cells.
JPEG Image - 106.1 KB - MD5: a6e64aba44186049ef675d59961a5e92
Figure 3 Sirp-a staining for panel A
JPEG Image - 82.5 KB - MD5: 4a6d9d3d67046283ee74be72cfb01ee0
Supplementary Figure S1 SIRP-A staining for Panel A
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