David Reich Lab Dataverse

Datasets in this collection support research conducted in the David Reich Lab at Harvard Medical School: https://reich.hms.harvard.edu/

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1 to 8 of 8 Results

A genomic history of the North Pontic Region from the Neolithic to the Bronze Age Oct 22, 2024 Nikitin, Alexey G.; Lazaridis, Iosif; Reich, David, 2024, "A genomic history of the North Pontic Region from the Neolithic to the Bronze Age", https://doi.org/10.7910/DVN/CJTV3Q, Harvard Dataverse, V1 The North Pontic Region was the meeting point of the farmers of Old Europe and the foragers and pastoralists of the Eurasian steppe, and the source of migrations deep into Europe. We report genome-wide data from 81 prehistoric North Pontic individuals to understand the genetic makeup of its people. North Pontic foragers had ancestry not only from B...
The Genetic Origin of the Indo-Europeans Oct 22, 2024 Lazaridis, Iosif; Patterson, Nick; Anthony, David; Vyazov, Leonid; Pinhasi, Ron; Reich, David, 2024, "The Genetic Origin of the Indo-Europeans", https://doi.org/10.7910/DVN/QGNMRH, Harvard Dataverse, V1 The Yamnaya archaeological complex appeared around 3300 BCE across the steppes north of the Black and Caspian Seas, and by 3000 BCE reached its maximal extent from Hungary in the west to Kazakhstan in the east. To localize Yamnaya origins among preceding Eneolithic people, we assembled ancient DNA from 428 individuals, demonstrating three genetic c...
The Allen Ancient DNA Resource (AADR): A curated compendium of ancient human genomes Sep 16, 2024 Mallick, Swapan; Reich, David, 2023, "The Allen Ancient DNA Resource (AADR): A curated compendium of ancient human genomes", https://doi.org/10.7910/DVN/FFIDCW, Harvard Dataverse, V9 The Allen Ancient DNA Resource (AADR) seeks to provide a publicly available, uniformly curated dataset that is maximally useful for scientists carrying out analyses of population history and natural selection. The dataset consists of thousands of ancient and present-day individuals genotyped at up to 1.23 million positions in the genome (in hg19 co...
Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation Sep 14, 2024 Akbari, Ali; David Reich, 2024, "Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation", https://doi.org/10.7910/DVN/7RVV9N, Harvard Dataverse, V1 We present a method for detecting evidence of natural selection in ancient DNA time series data that leverages an opportunity not utilized in previous scans: testing for a consistent trend in allele frequency change over time. By applying this to 8433 West Eurasians who lived over the past 14000 years and 6510 contemporary people, we find an order...
Data for Genetic Continuity and Change Among the Indigenous Peoples of California Sep 24, 2023 Nakatsuka, Nathan, 2023, "Data for Genetic Continuity and Change Among the Indigenous Peoples of California", https://doi.org/10.7910/DVN/Z2JD58, Harvard Dataverse, V1 Prior to colonialism, California harbored more language variation than all of Europe, and linguistic and archaeological analysis have led to many hypotheses to explain this diversity. We report genome-wide data from 79 ancient Californians and 40 ancient northern Mexicans dating to 7400-200 years before present (BP). Our analyses document long-term...
Data for: Entwined African and Asian Genetic Roots of Medieval Peoples of the Swahili Coast Jan 5, 2023 Brielle, Esther S.; Fleisher, Jeffrey; Waynne-Jones, Stephanie; Sirak, Kendra; Broomandkhoshbacht, Nasreen; Callan, Kim; Curtis, Elizabeth; Iliev, Lora; Lawson, Ann Marie; Oppenheimer, Jonas; Qiu, Lijun; Stewardson, Kristin; Workman, Noah J.; Zalzala, Fatma; Ayodo, George; Gidna, Agness O.; Kabiru, Angela; Kwekason, Amadus; Mabula, Audax Z.P.; Manthi, Fredrick K.; Ndiema, Emmanuel; Ogola, Christine; Sawchuk, Elizabeth; Al-Gazali, Lihadh; Ali, Bassam R.; Ben-Salam, Salma; Letellier, Thierry; Pierron, Denis; Radimilahy, Chantal; Rakotoarisoa, Jean-Aimé; Raaum, Ryan L.; Culleton, Brendan; Mallick, Swapan; Rohland, Nadin; Patterson, Nick; Mwenje, Mohammad Ali; Ahmed, Khalfan Bini; Mohamed, Mohamed Mchulla; Williams, Sloan; Monge, Janet; Kusimba, Sibel; Prendergast, Mary E.; Reich, David; Kusimba, Chapurukha M., 2023, "Data for: Entwined African and Asian Genetic Roots of Medieval Peoples of the Swahili Coast", https://doi.org/10.7910/DVN/NC28XW, Harvard Dataverse, V1 The urban peoples of the Swahili coast traded across eastern Africa and the Indian Ocean and were among the first sub-Saharan practitioners of Islam. The extent to which these early interactions between Africans and non-Africans were accompanied by genetic exchange remains unknown. We report ancient DNA data for 80 individuals from six medieval and...
The genetic history of the Southern Arc: A bridge between West Asia and Europe Aug 25, 2022 Lazaridis, Iosif; Alpaslan-Roodenberg, Songül; Pinhasi, Ron; Reich, David, 2022, "The genetic history of the Southern Arc: A bridge between West Asia and Europe", https://doi.org/10.7910/DVN/3AR0CD, Harvard Dataverse, V1 By sequencing 727 ancient individuals from the Southern Arc (Anatolia and its neighbors in Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic period and Bronze Age (about 5000 to 1000 BCE), when extensive gene flow entangled it with the Eurasian steppe. Two streams of migration transmitted Caucasus and Anatolian...
Data for: "Ancient DNA Reveals Five Streams of Migration into Micronesia and Matrilocality in Early Pacific Seafarers" Jun 15, 2022 Liu, Yue-Chen; Hunter-Anderson, Rosalind; Cheronet, Olivia; Eakin, Joanne; Camacho, Frank; Pietrusewsky, Michael; Rohland, Nadin; Ioannidis, Alexander; Athens, Stephen J.; Douglas, Michele Toomay; Ikehara-Quebral, Rona Michi; Bernardos, Rebecca; Culleton, Brendan J.; Mah, Matthew; Adamski, Nicole; Broomandkhoshbacht, Nasreen; Callan, Kimberly; Lawson, Ann Marie; Mandl, Kirsten; Michel, Megan; Oppenheimer, Jonas; Stewardson, Kristin; Zalzala, Fatma; Kidd, Kenneth; Kidd, Judith; Schurr, Theodore G.; Auckland, Kathryn; Hill, Adrian V. S.; Mentzer, Alexander J.; Quinto-Cortés, Consuelo D.; Robson, Kathryn; Kennett, Douglas J.; Patterson, Nick; Bustamante, Carlos D.; Moreno-Estrada, Andrés; Spriggs, Matthew; Vilar, Miguel; Lipson, Mark; Pinhasi, Ron; Reich, David, 2022, "Data for: "Ancient DNA Reveals Five Streams of Migration into Micronesia and Matrilocality in Early Pacific Seafarers"", https://doi.org/10.7910/DVN/63QFEC, Harvard Dataverse, V1 Micronesia began to be peopled earlier than other parts of Remote Oceania, but its inhabitants’ origins remain unclear. We generated genome-wide data from 164 ancient and 112 modern individuals. Analysis reveals five migratory streams into Micronesia. Three are East Asian-related, one is Polynesian, and a fifth is a Papuan source related to mainlan...

A genomic history of the North Pontic Region from the Neolithic to the Bronze Age

Oct 22, 2024

Nikitin, Alexey G.; Lazaridis, Iosif; Reich, David, 2024, "A genomic history of the North Pontic Region from the Neolithic to the Bronze Age", https://doi.org/10.7910/DVN/CJTV3Q, Harvard Dataverse, V1

The North Pontic Region was the meeting point of the farmers of Old Europe and the foragers and pastoralists of the Eurasian steppe, and the source of migrations deep into Europe. We report genome-wide data from 81 prehistoric North Pontic individuals to understand the genetic makeup of its people. North Pontic foragers had ancestry not only from B...

The Genetic Origin of the Indo-Europeans

Oct 22, 2024

Lazaridis, Iosif; Patterson, Nick; Anthony, David; Vyazov, Leonid; Pinhasi, Ron; Reich, David, 2024, "The Genetic Origin of the Indo-Europeans", https://doi.org/10.7910/DVN/QGNMRH, Harvard Dataverse, V1

The Yamnaya archaeological complex appeared around 3300 BCE across the steppes north of the Black and Caspian Seas, and by 3000 BCE reached its maximal extent from Hungary in the west to Kazakhstan in the east. To localize Yamnaya origins among preceding Eneolithic people, we assembled ancient DNA from 428 individuals, demonstrating three genetic c...

The Allen Ancient DNA Resource (AADR): A curated compendium of ancient human genomes

Sep 16, 2024

Mallick, Swapan; Reich, David, 2023, "The Allen Ancient DNA Resource (AADR): A curated compendium of ancient human genomes", https://doi.org/10.7910/DVN/FFIDCW, Harvard Dataverse, V9

The Allen Ancient DNA Resource (AADR) seeks to provide a publicly available, uniformly curated dataset that is maximally useful for scientists carrying out analyses of population history and natural selection. The dataset consists of thousands of ancient and present-day individuals genotyped at up to 1.23 million positions in the genome (in hg19 co...

Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation

Sep 14, 2024

Akbari, Ali; David Reich, 2024, "Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation", https://doi.org/10.7910/DVN/7RVV9N, Harvard Dataverse, V1

We present a method for detecting evidence of natural selection in ancient DNA time series data that leverages an opportunity not utilized in previous scans: testing for a consistent trend in allele frequency change over time. By applying this to 8433 West Eurasians who lived over the past 14000 years and 6510 contemporary people, we find an order...

Data for Genetic Continuity and Change Among the Indigenous Peoples of California

Sep 24, 2023

Nakatsuka, Nathan, 2023, "Data for Genetic Continuity and Change Among the Indigenous Peoples of California", https://doi.org/10.7910/DVN/Z2JD58, Harvard Dataverse, V1

Prior to colonialism, California harbored more language variation than all of Europe, and linguistic and archaeological analysis have led to many hypotheses to explain this diversity. We report genome-wide data from 79 ancient Californians and 40 ancient northern Mexicans dating to 7400-200 years before present (BP). Our analyses document long-term...

Data for: Entwined African and Asian Genetic Roots of Medieval Peoples of the Swahili Coast

Jan 5, 2023

Brielle, Esther S.; Fleisher, Jeffrey; Waynne-Jones, Stephanie; Sirak, Kendra; Broomandkhoshbacht, Nasreen; Callan, Kim; Curtis, Elizabeth; Iliev, Lora; Lawson, Ann Marie; Oppenheimer, Jonas; Qiu, Lijun; Stewardson, Kristin; Workman, Noah J.; Zalzala, Fatma; Ayodo, George; Gidna, Agness O.; Kabiru, Angela; Kwekason, Amadus; Mabula, Audax Z.P.; Manthi, Fredrick K.; Ndiema, Emmanuel; Ogola, Christine; Sawchuk, Elizabeth; Al-Gazali, Lihadh; Ali, Bassam R.; Ben-Salam, Salma; Letellier, Thierry; Pierron, Denis; Radimilahy, Chantal; Rakotoarisoa, Jean-Aimé; Raaum, Ryan L.; Culleton, Brendan; Mallick, Swapan; Rohland, Nadin; Patterson, Nick; Mwenje, Mohammad Ali; Ahmed, Khalfan Bini; Mohamed, Mohamed Mchulla; Williams, Sloan; Monge, Janet; Kusimba, Sibel; Prendergast, Mary E.; Reich, David; Kusimba, Chapurukha M., 2023, "Data for: Entwined African and Asian Genetic Roots of Medieval Peoples of the Swahili Coast", https://doi.org/10.7910/DVN/NC28XW, Harvard Dataverse, V1

The urban peoples of the Swahili coast traded across eastern Africa and the Indian Ocean and were among the first sub-Saharan practitioners of Islam. The extent to which these early interactions between Africans and non-Africans were accompanied by genetic exchange remains unknown. We report ancient DNA data for 80 individuals from six medieval and...

The genetic history of the Southern Arc: A bridge between West Asia and Europe

Aug 25, 2022

Lazaridis, Iosif; Alpaslan-Roodenberg, Songül; Pinhasi, Ron; Reich, David, 2022, "The genetic history of the Southern Arc: A bridge between West Asia and Europe", https://doi.org/10.7910/DVN/3AR0CD, Harvard Dataverse, V1

By sequencing 727 ancient individuals from the Southern Arc (Anatolia and its neighbors in Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic period and Bronze Age (about 5000 to 1000 BCE), when extensive gene flow entangled it with the Eurasian steppe. Two streams of migration transmitted Caucasus and Anatolian...

Data for: "Ancient DNA Reveals Five Streams of Migration into Micronesia and Matrilocality in Early Pacific Seafarers"

Jun 15, 2022

Liu, Yue-Chen; Hunter-Anderson, Rosalind; Cheronet, Olivia; Eakin, Joanne; Camacho, Frank; Pietrusewsky, Michael; Rohland, Nadin; Ioannidis, Alexander; Athens, Stephen J.; Douglas, Michele Toomay; Ikehara-Quebral, Rona Michi; Bernardos, Rebecca; Culleton, Brendan J.; Mah, Matthew; Adamski, Nicole; Broomandkhoshbacht, Nasreen; Callan, Kimberly; Lawson, Ann Marie; Mandl, Kirsten; Michel, Megan; Oppenheimer, Jonas; Stewardson, Kristin; Zalzala, Fatma; Kidd, Kenneth; Kidd, Judith; Schurr, Theodore G.; Auckland, Kathryn; Hill, Adrian V. S.; Mentzer, Alexander J.; Quinto-Cortés, Consuelo D.; Robson, Kathryn; Kennett, Douglas J.; Patterson, Nick; Bustamante, Carlos D.; Moreno-Estrada, Andrés; Spriggs, Matthew; Vilar, Miguel; Lipson, Mark; Pinhasi, Ron; Reich, David, 2022, "Data for: "Ancient DNA Reveals Five Streams of Migration into Micronesia and Matrilocality in Early Pacific Seafarers"", https://doi.org/10.7910/DVN/63QFEC, Harvard Dataverse, V1

Micronesia began to be peopled earlier than other parts of Remote Oceania, but its inhabitants’ origins remain unclear. We generated genome-wide data from 164 ancient and 112 modern individuals. Analysis reveals five migratory streams into Micronesia. Three are East Asian-related, one is Polynesian, and a fifth is a Papuan source related to mainlan...

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